Principal Research Scientist, Analytical Chemistry

Role: Principal Research Scientist in Analytical Chemistry at IDEAYA Biosciences, leading discovery analytical efforts for small molecule drug candidates in oncology. Responsibilities include overseeing compound purification (HPLC, SFC), structural elucidation, physicochemical property analysis, method development/validation, troubleshooting, equipment management, and external CRO oversight. The role involves managing and mentoring junior staff, aligning analytical strategies across teams, and adopting emerging techniques. Requirements: Ph.D. in analytical chemistry or related field, 5+ years in drug discovery, with expertise in small molecule purification, physicochemical analysis, and CRO management. Preferred: experience in structural elucidation techniques. High-value: focus on small molecules for oncology, with responsibilities spanning discovery pipeline stages, analytical method development, and cross-functional collaboration. Location: South San Francisco, onsite four days/week; work involves regular communication with medicinal chemistry and project teams.