Principal Research Associate, mRNA Process Development

Role Summary

Seeking a Principal Research Associate to join the mRNA Process Development team. The role involves executing late-stage mRNA process development activities with a focus on downstream purification, and supporting experimental design, execution, data analysis, and authoring technical documents and reports. This position is onsite 5 days per week in Cambridge, MA.

Responsibilities

• Support the design and execution of mRNA purification studies to support process development
• Use DoE and other statistical tools to help characterize our processes and to develop control strategies
• Help manufacture materials for use in process development
• Support external and internal tech transfers
• Effectively document, interpret and communicate technical results
• Work cross-functionally to support Beam programs to ensure critical timelines are met

Qualifications

• Bachelor’s or Master’s Degree in related science with 10 years of relevant experience (e.g. chemical engineering, biochemical engineering, biochemistry etc)
• Experience with mRNA purification technologies is preferred (chromatography and TFF)
• Knowledge of mRNA manufacturing processes
• Highly organized and detail oriented with strong communication skills
• Motivated to learn and to execute process development studies in the lab
• A collaborative mindset