Principal Manager, Clinical Operations Lead

Role: Principal Manager, Clinical Operations Lead overseeing US regional clinical trial execution in cancer immunotherapy programs targeting PRAME. Responsibilities: lead trial delivery from start-up to completion, oversee CROs and vendors, manage cross-functional stakeholder collaboration (Clinical Development, Regulatory, Safety, Biometrics, Supply Chain), and mentor clinical operations staff; contribute to process improvements and inspection readiness. Requirements: Bachelor's degree in life sciences or related field; 7+ years of global clinical operations leadership, with experience in late-phase or launch oncology programs, cell/gene therapy, or complex biologics; strong vendor management and cross-functional collaboration skills. Preferred: Master’s degree; proven success in biologics/oncology clinical trial management, operational excellence initiatives, and navigating complex development processes. HighValue: US-based, fully remote, oncology (cell/gene therapy, biologics), late-phase or launch, clinical trial oversight, CRO/vendor management, cross-functional stakeholder engagement. WorkSetup: fully remote, no specific travel requirements stated.