Principal Investigator, Translational Biomarker Discovery Laboratory

Role: Senior translational scientist leading assay development and biomarker discovery to bridge preclinical and early clinical research in oncology and inflammation/autoimmunity. Responsibilities: design and implement multi-omic assays (transcriptomics, proteomics, spatial biology), analyze patient-derived multi-omic data, and support therapeutic target validation, mechanism elucidation, and dose optimization. Collaborates with bioinformatics and clinical teams to translate complex data into actionable insights, contributes to early toxicology and safety biomarker identification, and provides scientific leadership within the lab, potentially overseeing a small team. Qualifications: PhD in Oncology, Molecular Biology, Immunology, or related field; 3-10 years of experience in translational research within pharma/biotech; strong hands-on expertise in advanced molecular/cellular technologies, assay development, and multi-omics platforms; experience working with human samples and model systems; excellent communication skills. Preferred: biomarker strategy support for early clinical programs; familiarity with oncology or autoimmune disease biology; experience collaborating with toxicology or regulatory functions; ability to work autonomously while leading technical efforts. High-value specifics include focus on oncology and inflammatory/autoimmune indications, early-stage translational programs, and integration of multi-omic data to inform drug development. Work setup details not explicitly provided.