Principal Biostatistician

Role: Senior Biostatistician supporting Entrada Therapeutics' clinical-stage biopharma programs, focusing on genetic medicines for neuromuscular and retinal diseases. Responsibilities include developing statistical strategies for multiple DMD programs and DM1 collaboration, designing protocols, overseeing statistical deliverables, reviewing data management and randomization processes, and contributing to regulatory documents and scientific publications. The role also involves vendor management, innovating analytical methodologies, and supporting department strategies. Requirements: Ph.D. in Statistics or related field, 6+ years of biotech/pharma industry experience, strong expertise in statistical analysis, programming (R, SAS, Python), and regulatory guidelines (CDISC, SDTM, ADaM). Preferred: experience in neuromuscular or ophthalmology therapeutics, familiarity with machine learning and AI, vendor management skills. The position is remote within the US, with quarterly travel to Boston, MA. The role emphasizes collaboration across teams, innovation in statistical approaches, and contributes to a pipeline targeting exon skipping in DMD and myotonic dystrophy. High-value details include the focus on genetic medicines, rare diseases, early to mid-stage clinical development, and cross-functional engagement with development, data management, and regulatory teams.