Principal, Biostatistician

Role: Principal Biostatistician responsible for leading statistical analysis connecting clinical trial data to key pipeline and commercial decisions at Roivant. Objectives include rigorous analysis of efficacy, safety, and subgroup signals from clinical datasets, building statistical frameworks, and synthesizing evidence to inform high-stakes decisions. Responsibilities: analyze patient-level trial data, develop models (mixed-effects, Bayesian), monitor safety signals, challenge clinical assumptions, and execute rapid analytical sprints; develop comprehensive evidence narratives by evaluating internal and external data, including competitor trials and literature; drive data infrastructure development across platforms and therapeutic areas. Requirements: advanced degree in biostatistics, statistics, epidemiology, or related field; proven experience with clinical trial data, including patient-level datasets; expertise in statistical methods (e.g., mixed-effects, Bayesian, sensitivity analyses); knowledge of clinical trial design and regulatory frameworks (ICH E9, estimands); demonstrated ability to translate analysis into decision-making and communicate findings clearly to executive stakeholders. Preferred: direct clinical trial statistical experience. High-Value: focus on clinical evidence interpretation for pipeline assets, supporting imminent product launches; role offers significant ownership, exposure to senior leadership, and growth potential within a biopharma context. Work setup: full-time, with a competitive salary range ($130K–$220K) and equity; location details unspecified. The role emphasizes high-impact, data-driven decision support in a fast-paced biotech environment.