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Principal Automation Engineer

Takeda
August 22, 2026
Full-time
Remote friendly (Lexington, MA)
Worldwide
$242,550 - $242,550 USD yearly
Operations
Role: Principal Automation Engineer supporting cGMP manufacturing processes at Takeda’s Lexington, MA site, focusing on operational, project, and strategic automation system support. Responsibilities: oversee PLC, DCS, Manufacturing Execution Systems, and ancillary data systems for equipment such as bioreactors, chromatography skids, filtration units, and autoclaves; lead technical development, system upgrades, lifecycle planning, and innovation; serve as subject matter expert across multiple platform operations; support large-scale project engineering, vendor management, and industry best practices. Requirements: Bachelor’s in Electronics Engineering with 12+ years of experience in large-scale control systems (>100K I/O signals), control system lifecycle, upgrades, virtualization, third-party integrations, cybersecurity, and SOP development; proven leadership in complex automation environments. HighValue: biopharma manufacturing, cGMP compliance, control systems, process automation, large-scale site operations, and project leadership. WorkSetup: full-time, remote options up to 20%, with up to 20% domestic/international travel.