Preclinical Safety Profiling lab associate, Senior Scientist (Dual Level Posting)
Novartis
August 25, 2026
On-site
Cambridge, MA
Clinical Research and Development
Key Responsibilities:
- Perform in-vitro biochemical and cell-based experiments to clarify and mitigate off-target activities leading to “go” or “no go” decisions.
- Maintain cell lines and support ongoing experiments.
- Independently develop assays to implement project strategy.
- Experience with radioactivity is advantageous.
- Experience with stand-alone automation and readers (e.g., Felix, ECHO, µCELL, Envision, Microbeta).
- Interest in identifying and evaluating new assay technologies.
- Support all small molecule projects from early discovery through to preclinical candidates and beyond.
- Communicate with stakeholders, including experimental design, data quality, and timeline requirements.
- Participate in cross-functional early safety screening & profiling collaborations to support early derisking of compounds, drug targets, and therapeutic modalities.
- Deliver clear presentations to audiences with different expertise.
- Ensure quality and compliance of data generation, analyses, and resultant reports.
Essential Requirements:
- BS with 5+ years relevant experience, or MVSc/MS/M.Pharm with 2+ years relevant work in pharmacology/toxicology.
- Understand hazard identification and risk assessment for off-target mitigation.
- Familiar with early drug discovery processes.
- Experience with data integrity and quality assurance practices.
- Excellent communication skills; translate analytical concepts for diverse stakeholders.
- Provide solutions/recommendations to business users; concise, effective communication for non-technical teams.
- Coordinate/prioritize resources, manage change, anticipate risks, and resolve issues.
- Collaborate with internal and cross-functional teams to solve business problems and propose efficiencies/innovative approaches.
- Familiar with visualization tools.
- Team player; continuous learning.
Compensation & Benefits:
- Performance-based cash incentive; eligibility for annual equity awards depending on level.
- Comprehensive benefits for US-based eligible employees (health, life, disability, 401(k) match, time off).
Application Instructions:
- For reasonable accommodations, email [email protected] or call +1(877)395-2339; include job requisition number.
- Perform in-vitro biochemical and cell-based experiments to clarify and mitigate off-target activities leading to “go” or “no go” decisions.
- Maintain cell lines and support ongoing experiments.
- Independently develop assays to implement project strategy.
- Experience with radioactivity is advantageous.
- Experience with stand-alone automation and readers (e.g., Felix, ECHO, µCELL, Envision, Microbeta).
- Interest in identifying and evaluating new assay technologies.
- Support all small molecule projects from early discovery through to preclinical candidates and beyond.
- Communicate with stakeholders, including experimental design, data quality, and timeline requirements.
- Participate in cross-functional early safety screening & profiling collaborations to support early derisking of compounds, drug targets, and therapeutic modalities.
- Deliver clear presentations to audiences with different expertise.
- Ensure quality and compliance of data generation, analyses, and resultant reports.
Essential Requirements:
- BS with 5+ years relevant experience, or MVSc/MS/M.Pharm with 2+ years relevant work in pharmacology/toxicology.
- Understand hazard identification and risk assessment for off-target mitigation.
- Familiar with early drug discovery processes.
- Experience with data integrity and quality assurance practices.
- Excellent communication skills; translate analytical concepts for diverse stakeholders.
- Provide solutions/recommendations to business users; concise, effective communication for non-technical teams.
- Coordinate/prioritize resources, manage change, anticipate risks, and resolve issues.
- Collaborate with internal and cross-functional teams to solve business problems and propose efficiencies/innovative approaches.
- Familiar with visualization tools.
- Team player; continuous learning.
Compensation & Benefits:
- Performance-based cash incentive; eligibility for annual equity awards depending on level.
- Comprehensive benefits for US-based eligible employees (health, life, disability, 401(k) match, time off).
Application Instructions:
- For reasonable accommodations, email [email protected] or call +1(877)395-2339; include job requisition number.