Postdoctoral Fellow - Neurology Research
Ionis Pharmaceuticals, Inc.
August 21, 2026
On-site
Carlsbad, CA
Clinical Research and Development
Summary
We are seeking a Postdoctoral Fellow in Neurology Research to investigate the cellular and molecular mechanisms underlying white matter injury and repair. The successful candidate will develop and apply innovative cellular and animal models to identify and validate therapeutic targets that promote oligodendrocyte maturation and remyelination.
Work Location: Onsite Carlsbad
Responsibilities
- Design and execute research to investigate mechanisms underlying white matter injury and repair.
- Develop and apply cellular and animal models to study disease biology and evaluate therapeutic hypotheses.
- Employ molecular, cellular, imaging, and OMICS approaches to identify and validate novel therapeutic targets.
- Analyze, interpret, and communicate experimental findings to multidisciplinary project teams.
- Publish research in peer-reviewed journals and present findings at internal and external scientific meetings.
Requirements
- Ph.D. in Neurobiology, Cell Biology, or related discipline with a strong publication record.
- Strong organizational, communication, and problem-solving skills; ability to work independently and collaboratively.
- Include a CV and cover letter.
Preferred/Advantageous
- Experience in oligodendrocyte biology, myelination, developmental neuroscience, or related neurobiology (highly desirable).
- Experience with human iPSC culture/differentiation, primary neural cell cultures, or advanced in vitro models (preferred).
- Transcriptomic/translational profiling, single-cell RNA sequencing, or other OMICS approaches (advantageous).
- Molecular biology: qPCR, RNA analysis, immunocytochemistry/immunohistochemistry, fluorescence/confocal microscopy (advantageous).
- Rodent models, tissue processing, and histological analyses (beneficial).
Application
Apply online referencing requisition #IONIS004012.
Benefits/Pay
- Pay scale: $65,000 to $87,000.
We are seeking a Postdoctoral Fellow in Neurology Research to investigate the cellular and molecular mechanisms underlying white matter injury and repair. The successful candidate will develop and apply innovative cellular and animal models to identify and validate therapeutic targets that promote oligodendrocyte maturation and remyelination.
Work Location: Onsite Carlsbad
Responsibilities
- Design and execute research to investigate mechanisms underlying white matter injury and repair.
- Develop and apply cellular and animal models to study disease biology and evaluate therapeutic hypotheses.
- Employ molecular, cellular, imaging, and OMICS approaches to identify and validate novel therapeutic targets.
- Analyze, interpret, and communicate experimental findings to multidisciplinary project teams.
- Publish research in peer-reviewed journals and present findings at internal and external scientific meetings.
Requirements
- Ph.D. in Neurobiology, Cell Biology, or related discipline with a strong publication record.
- Strong organizational, communication, and problem-solving skills; ability to work independently and collaboratively.
- Include a CV and cover letter.
Preferred/Advantageous
- Experience in oligodendrocyte biology, myelination, developmental neuroscience, or related neurobiology (highly desirable).
- Experience with human iPSC culture/differentiation, primary neural cell cultures, or advanced in vitro models (preferred).
- Transcriptomic/translational profiling, single-cell RNA sequencing, or other OMICS approaches (advantageous).
- Molecular biology: qPCR, RNA analysis, immunocytochemistry/immunohistochemistry, fluorescence/confocal microscopy (advantageous).
- Rodent models, tissue processing, and histological analyses (beneficial).
Application
Apply online referencing requisition #IONIS004012.
Benefits/Pay
- Pay scale: $65,000 to $87,000.