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Postdoctoral Fellow - AI/ML Upstream Cell Culture Modeling & Process Development

Eli Lilly and Company
September 23, 2026
Full-time
On-site
Indianapolis, IN
Operations
Role: Postdoctoral Fellow in Upstream Process Development focusing on mammalian cell culture for bioprocessing of recombinant proteins, supporting early- and late-phase clinical trials. Responsibilities: develop and calibrate mechanistic and hybrid metabolic models, design and execute cell culture experiments, utilize machine learning and omics data integration to predict and optimize cellular performance, and explore AI-assisted process control approaches. Requirements: PhD in Bioengineering, Systems Biology, or related field; experience with metabolic modeling, cell culture experiments (batch, fed-batch), and proficiency in Python or MATLAB; authorized to work in the US. Preferred: strong foundation in cell physiology, process control concepts, analytical chemistry techniques, and data-driven modeling. HighValue: biologics, mammalian (e.g., CHO) cell processes, early- and late-phase clinical development, computational modeling, and bioprocess optimization. Collaboration with analytical teams and cross-functional groups. Work setup: laboratory environment, fixed-duration two-year program with potential extension.