Post-Doctoral Scientist– Molecular Pharmacology

Role: Post-doctoral scientist in Molecular Pharmacology within Lilly's Small Molecule Discovery and Cardiometabolic research units, focusing on mitochondrial uncouplers for metabolic disease. Responsibilities: develop/validate assays to identify small molecule uncouplers, characterize their bioenergetic activity across cell types and systems, design/execute screens for novel compounds, and analyze mechanisms of action, potency, and safety. Collaborate with bioenergetics, pharmacology, and metabolic biology experts; present research findings and publish. Requirements: Ph.D. in Molecular Biology, Biochemistry, Cell Biology, Pharmacology, or related field; experience with molecular biology techniques, high-throughput assay platforms, and cell-based imaging; authorized to work in the U.S. Full-time role with a salary range of $58,000-$123,200. Preferred skills include CRISPR/Cas9 editing, target engagement assays (e.g., CETSA, NanoBRET), proteomics, and chemical biology. High-value specifics: focus on mitochondrial uncoupling relevant to metabolic disorders; assay development and bioenergetics research; emphasis on innovative screening techniques. Work setup: not specified, but likely research lab environment.