PK/PD Senior Scientist
Zoetis
4 hours ago
Remote friendly (Michigan, United States)
United States
Clinical Research and Development
POSITION RESPONSIBILITIES:
- Design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
- Provide PK and PK/PD modeling and simulation to select lead candidates and optimize dose regimens.
- Collaborate with the bioanalytical team to assess analytical assay suitability and forecast analytical requirements.
- Lead scientific strategy development across therapeutic areas, focusing on mechanistic platforms/biomarkers to support translation, target engagement, and dose regimen predictions.
- Collaborate with multidisciplinary teams to design and conduct studies aligned with project strategy.
- Present research results to scientific teams, management, and regulatory agencies.
- Write sections of regulatory submissions, respond to regulatory inquiries, and maintain knowledge of regulatory guidance.
REQUIRED EDUCATION AND EXPERIENCE:
- Ph.D. in pharmacology, pharmaceutical sciences, biochemistry, or related field. 2–4 years post-doctoral experience in pharmaceutical development is highly desirable. DVM DACVCP or DVM Dipl. ECVPT is highly desirable.
- Proven ability to design, analyze, and interpret in vivo PK and PK/PD studies; biotherapeutics (protein therapeutics) experience is highly desirable.
- Skilled in PK/PK/PD analysis software such as WinNonlin, Monolix, or Watson.
- Excellent verbal and written communication skills.
- Self-starter who can prioritize work and work efficiently with minimal supervision.
- Working knowledge of bioanalytical methodology.
- PK/PD modeling and simulation experience (e.g., PBPK, QSP, population PK modeling with NONMEM, R, or related tools) is highly desirable.
Compensation/Benefits:
- US base salary range: $114,000–$185,000.
- Eligible for short-term and long-term incentives.
- Comprehensive benefits including healthcare/insurance day one, 401(k) with match and profit-sharing, and 4 weeks of vacation.
- Design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
- Provide PK and PK/PD modeling and simulation to select lead candidates and optimize dose regimens.
- Collaborate with the bioanalytical team to assess analytical assay suitability and forecast analytical requirements.
- Lead scientific strategy development across therapeutic areas, focusing on mechanistic platforms/biomarkers to support translation, target engagement, and dose regimen predictions.
- Collaborate with multidisciplinary teams to design and conduct studies aligned with project strategy.
- Present research results to scientific teams, management, and regulatory agencies.
- Write sections of regulatory submissions, respond to regulatory inquiries, and maintain knowledge of regulatory guidance.
REQUIRED EDUCATION AND EXPERIENCE:
- Ph.D. in pharmacology, pharmaceutical sciences, biochemistry, or related field. 2–4 years post-doctoral experience in pharmaceutical development is highly desirable. DVM DACVCP or DVM Dipl. ECVPT is highly desirable.
- Proven ability to design, analyze, and interpret in vivo PK and PK/PD studies; biotherapeutics (protein therapeutics) experience is highly desirable.
- Skilled in PK/PK/PD analysis software such as WinNonlin, Monolix, or Watson.
- Excellent verbal and written communication skills.
- Self-starter who can prioritize work and work efficiently with minimal supervision.
- Working knowledge of bioanalytical methodology.
- PK/PD modeling and simulation experience (e.g., PBPK, QSP, population PK modeling with NONMEM, R, or related tools) is highly desirable.
Compensation/Benefits:
- US base salary range: $114,000–$185,000.
- Eligible for short-term and long-term incentives.
- Comprehensive benefits including healthcare/insurance day one, 401(k) with match and profit-sharing, and 4 weeks of vacation.