PK/PD Principal Scientist
Zoetis
August 18, 2026
Remote friendly (Michigan, United States)
United States
Clinical Research and Development
POSITION RESPONSIBILITIES:
- Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
- Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
- Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements.
- Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid translation, measurement of target engagement, and dose regimen predictions.
- Work collaboratively with multidisciplinary teams to design and prosecute studies in line with project strategy.
- Present research results to scientific teams, management, and regulatory agencies.
- Write sections of regulatory submissions, respond to regulatory inquiries, and maintain knowledge of regulatory guidance.
REQUIRED EDUCATION AND EXPERIENCE:
- Ph.D in pharmacology, biochemistry, or related field with 4+ years of relevant pharmaceutical development experience; DVM DACVCP or DVM Dipl. ECVPT highly desirable.
- Proven ability to design, analyze and interpret in vivo PK and PK/PD studies; biotherapeutics/protein therapeutics experience highly desirable.
- Skilled in PK/PKPD analysis software (e.g., WinNonlin, Monolix, Watson).
- Excellent verbal and written communication.
- Self-starter; can prioritize and work with minimal supervision.
- Working knowledge of bioanalytical methodology.
- Knowledge of ADA assays/immunogenicity of biotherapeutics highly desirable.
- PK/PD modeling and simulation (e.g., PBPK, QSP, population PK with NONMEM/R) highly desirable.
- Experience interacting with regulatory agencies highly desirable; GLP experience desirable.
BENEFITS/COMPENSATION:
- US base salary range: $114,000–$185,000.
- Eligible for short-term and long-term incentives.
- Comprehensive benefits including healthcare/insurance starting day one, 401K match and profit-sharing, and 4 weeks of vacation.
Application instructions:
- Visit zoetisbenefits.com to learn more.
- Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
- Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens.
- Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements.
- Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid translation, measurement of target engagement, and dose regimen predictions.
- Work collaboratively with multidisciplinary teams to design and prosecute studies in line with project strategy.
- Present research results to scientific teams, management, and regulatory agencies.
- Write sections of regulatory submissions, respond to regulatory inquiries, and maintain knowledge of regulatory guidance.
REQUIRED EDUCATION AND EXPERIENCE:
- Ph.D in pharmacology, biochemistry, or related field with 4+ years of relevant pharmaceutical development experience; DVM DACVCP or DVM Dipl. ECVPT highly desirable.
- Proven ability to design, analyze and interpret in vivo PK and PK/PD studies; biotherapeutics/protein therapeutics experience highly desirable.
- Skilled in PK/PKPD analysis software (e.g., WinNonlin, Monolix, Watson).
- Excellent verbal and written communication.
- Self-starter; can prioritize and work with minimal supervision.
- Working knowledge of bioanalytical methodology.
- Knowledge of ADA assays/immunogenicity of biotherapeutics highly desirable.
- PK/PD modeling and simulation (e.g., PBPK, QSP, population PK with NONMEM/R) highly desirable.
- Experience interacting with regulatory agencies highly desirable; GLP experience desirable.
BENEFITS/COMPENSATION:
- US base salary range: $114,000–$185,000.
- Eligible for short-term and long-term incentives.
- Comprehensive benefits including healthcare/insurance starting day one, 401K match and profit-sharing, and 4 weeks of vacation.
Application instructions:
- Visit zoetisbenefits.com to learn more.