Pharmacology Principal Research Associate
Vertex Pharmaceuticals
September 17, 2026
Full-time
On-site
Boston, MA
Other
Role: Pharmacology Principal Research Associate responsible for conducting high-quality ex vivo and in vivo experiments to evaluate compound effects on disease models, primarily focusing on immune and muscular dystrophy-related research. Responsibilities: design and execute independent experiments, lead flow cytometry and cell sorting workflows with ex vivo samples from rodent and large animal studies, perform animal handling, dosing via multiple routes, tissue dissection, sample collection, and basic bioanalytical assays such as ELISA; analyze data, troubleshoot protocols, contribute to publications and patents, and present findings. Requirements: Bachelorโs degree in biological sciences with 5+ years (or Masterโs with 2+ years) experience; expertise in flow cytometry, cell sorting, in vivo pharmacology techniques, and ELISA; strong analytical and troubleshooting skills; proficiency in experimental design, data interpretation, and scientific communication. HighValue: ex vivo/in vivo disease models, immunology, muscular dystrophy, pharmacology, flow cytometry, biofluid analysis, on-site role, with collaboration across research functions.