Oligo Chemistry and Biochemistry Co-op (Fall 2026)

Role Summary

Oligo Chemistry and Biochemistry Co-op (Fall 2026) is a co-op position at Wave Life Sciences in Cambridge, Massachusetts. The role offers exposure to areas of oligonucleotide chemistry and biochemistry/bioanalytical chemistry, with training across a variety of laboratory techniques and instrumentation. It is an opportunity for a motivated student to learn in a fast-paced, cross-disciplinary biotech environment, with strong organizational skills and attention to detail. Organic chemistry or biochemistry laboratory experience is preferred.

Responsibilities

• Assist in the upstream and downstream biochemical/bioanalytical and biological analysis of oligonucleotides
• Preparation of reagents and buffers for biochemical/bioanalytical and biological experiments by measuring the weight of organic compounds and the volume of solutions
• Preparation of buffer solutions of specified molarity for Liquid Chromatography (LC) analysis of oligonucleotides
• Assist in the operation of Liquid Chromatography Mass Spectrometry (LCMS) system and be able to learn and work on the system
• Assist in the physicochemical experiments (thermal denaturing experiment etc.) of oligonucleotides
• Maintain a detailed report of experimental procedures and findings in electronic lab notebooks
• Use of pH meter, Nanodrop to record data
• Use of MS Excel is preferred

Skills

• Present experimental data in team meetings
• Eager to learn about instrumentation and work with new technology
• Following the lab safety protocols including use of PPEs