Role Summary
Neuroscience Research Scientist will apply electrophysiology and neuropharmacology to characterize network dysfunction in neurodegenerative disease models. The role involves generating high-quality data from human iPSC-derived 2D and 3D models using functional readouts such as multi-electrode arrays and calcium imaging. You will design experiments, analyze complex neural datasets, and translate results into actionable insights within a collaborative, lab-based setting in Salt Lake City.
Responsibilities
- Serve as a hands-on technical expert, executing advanced neuropharmacology and electrophysiology studies on human iPSC-derived neurons and 2D/3D neurodegenerative disease models.
- Independently design, develop, and optimize cell-based functional assays to characterize drug candidates and profile new model systems.
- Conduct rigorous analysis, signal processing, and troubleshooting of complex neuroscience datasets (electrical traces, local field potentials, calcium traces, pharmacodynamic modeling).
- Document and present experimental designs, data, and actionable insights to cross-functional teams to drive program decisions.
- Manage key laboratory functions with attention to detail, including coordinating cross-functional lab work, monitoring inventory, ordering reagents, and basic equipment maintenance.
Qualifications
- Required: M.S. or B.S. in Neuroscience, Biology, or related field (Ph.D. not required) and 3–5 years of pharmaceutical or biotechnology experience with hands-on execution of advanced cellular neuropharmacology and electrophysiological studies, preferably in neurodegenerative diseases.
- Required: Direct hands-on experience with functional neuroscience techniques such as multielectrode arrays and other high-throughput electrophysiology platforms to characterize drug candidates and profile novel cellular model systems.
- Required: Hands-on expertise with human cell-based translatable systems, including iPSC-derived neurons and 2D or 3D in vitro neurodegenerative disease models.
- Required: Demonstrated ability to independently design, optimize, analyze, and present data related to cell-based functional assays; deep experience with electrical traces, local field potentials (LFP), or calcium imaging is highly desirable.
- Preferred: Knowledge and ability to execute general molecular biology techniques and assays for downstream protein and RNA processing.
Education
- M.S. or B.S. in Neuroscience, Biology, or related field (Ph.D. not required)