MS&T Senior Scientist - Small Molecule Drug Substance

Role: Senior Scientist in Manufacturing Science & Technology (MS&T), focusing on process chemistry in pharmaceutical development and commercial manufacturing. Responsibilities include managing technical transfer and collaborations with external CDMOs, executing synthetic organic experiments across development stages, monitoring reactions with analytical methods, and supporting regulatory documentation. The role requires interpreting complex chemistry, championing new technologies, and engaging in cross-functional teams with Analytical Sciences & Technology, Quality, and Regulatory departments. Requirements: Bachelor's in chemistry with 8+ years, or Master's with 5+ years, or PhD with 2-5 years in related fields like R&D or chemical manufacturing; proven synthetic chemistry skills; experience supporting CMC sections of INDs preferred. High-Value: expertise in process chemistry, GMP compliance, chemical transfer with CDMOs, and supporting regulatory submissions; international travel up to 20%; on-site at Vertex. The role emphasizes collaborative problem-solving, technical leadership, and regulatory adherence in a biotech manufacturing context.