Molecular & Cell Biology Senior Research Scientist

Role: Senior Research Scientist specializing in Molecular & Cell Biology within Vertex's Human Cell Models group, focused on developing human neuronal models for drug discovery. Responsibilities include designing and executing cellular and molecular studies, optimizing iPSC-derived neuronal systems, utilizing genome editing, automating stem cell workflows, and integrating multi-omic data. The role demands collaboration across research, screening, pharmacology, and computational teams to generate actionable insights supporting therapeutic development. Requirements: PhD in Stem Cell Biology, Neuroscience, or related field; at least four years postdoctoral or industry experience; deep expertise in iPSC reprogramming, neuronal differentiation, and cell-based assay development; proficiency with automation platforms and molecular biology techniques. Preferred skills encompass 3D cultures, organoids, high-content imaging, and data analysis tools like R or Python. High-value biopharma specifics include a focus on neuronal models for neurodegenerative or neurological diseases, support for early drug discovery stages, and operations in a GxP-compliant, multidisciplinary research setting. The position is on-site in Boston, with flexible ad hoc arrangements.