Modeling & Simulations Associate Director
Vertex Pharmaceuticals
August 29, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
Clinical Research and Development
Role: Associate Director of Modeling & Simulations leading cross-functional drug development teams to develop and implement M&S strategies. Responsibilities: design and execute PK/PD modeling, clinical trial simulations, and model-based analyses to inform study design, dose selection, and success probability; independently perform mechanism-based PKPD analyses; contribute to improving M&S capabilities and tools. Requirements: PhD or Masterβs with 6+ or 10+ years in pharmacometrics, PK/PD modeling, or related fields; expertise in population PK/PD, mechanistic modeling, and proficiency with NonMem, PsN, R, Phoenix; strong leadership, collaboration, and communication skills. HighValue: experience in clinical drug development, quantitative pharmacology, and modeling within biotech or pharma; ability to influence cross-functional teams; hybrid work flexibility. WorkSetup: hybrid or on-site; flexible schedule.