Medicinal Chemistry Research Scientist

Role Summary

Medicinal Chemistry Research Scientist at Vertex Pharmaceuticals. The role involves preparing single and focused sets of small organic molecules, developing and optimizing synthetic methods, and creating and interpreting project-relevant structure-activity relationships (SAR). The candidate should demonstrate expert understanding of organic reaction mechanisms, executable synthetic routes, and a balance of rational concepts with creativity, including developing new synthetic methodologies as needed. The successful candidate will work independently and collaboratively in teams, adapting to rapidly changing needs, and should have a strong desire to grow as a medicinal chemist with a passion for organic chemistry.

Responsibilities

• Maintain a high level of productivity in the laboratory setting
• Develops and executes clear synthetic routes using state-of-the-art synthetic methodologies
• Primarily responsible for executing organic syntheses in a timely, efficient, and independent manner
• Create and interpret SAR with a clear understanding of the biological data
• Organize and triage efforts to stay consistent with project priorities
• Clearly and effectively communicate ideas and results (both verbally and in writing) to a broad range of audiences

Knowledge

• Designs and executes complex, challenging chemistry experiments
• Demonstrates astute understanding of his/her own discipline and the relevant literature
• Maintains a high level of knowledge related to current developments in the scientific project field
• Displays proven productivity and experimental creativity, and effective dissemination of ideas
• Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations
• Demonstrates awareness of other project-related disciplines and an understanding of general concepts and some experimental detail within those areas

Education

• Ph.D. (or equivalent degree) in chemistry or related science with 0‚Äì3 years of relevant post-doctoral experience, or
• Master‚Äôs degree (or equivalent) in chemistry or related science with 3+ years of relevant employment experience, or
• Bachelor‚Äôs degree (or equivalent) in chemistry or related science with 6+ years of relevant employment experience
• Demonstrated effective communication skills, both verbal and written
• Ability to navigate and be successful in a fast-paced, highly matrixed work environment
• A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society

Additional Requirements

• On-Site Designated: five days per week on-site with ad hoc flexibility