Medical Director, Oncology Clinical Development

Role Summary

Medical Director, Oncology Clinical Development. Responsible for clinical research activities advancing GSK’s oncology portfolio, engaging in medical dialogues with scientific and medical leaders, and managing relationships with key external experts. Requires a physician to develop and execute oncology clinical trials supporting clinical development, regulatory filing, and initial market launch of innovative oncology agents. On-site presence 2–3 days a week in specified locations.

Responsibilities

• Collaborate with physicians, scientists, regulatory professionals, biostatisticians, regulatory, executive staff and others in a complex matrix environment to develop and execute phase 1-3 interventional clinical trials
• Ensure high quality protocol development aligned with the Clinical Development Plan to determine efficacy, safety, value to patient, and differentiation in the shortest timeframe
• Contribute to end-to-end clinical trial development to ensure scientific integrity and timely delivery aligned with regulatory approvals and lifecycle management, incorporating global considerations
• Interpret and summarize study results to define safety, efficacy, pharmacokinetic/pharmacodynamic, and patient-reported outcomes for the targeted population
• Assume medical responsibility for clinical trials with real-time medical monitoring, including eligibility assessment, design questions, and urgent safety questions
• Review clinical trial data and oversee blinded review of data packages for IDMCs
• Review/monitor safety data in collaboration with pharmacovigilance for active studies
• Participate in authoring clinical study reports and regulatory documents; collaborate with Regulatory Affairs, CMC, Toxicology, Research, Pharmacology to respond to health authority and ethics queries
• Collaborate with Principal Investigators on evaluation of publications associated with clinical data
• Develop long-term strategic partnerships with thought leaders to support GSK‚Äôs vision
• Understand biological mechanisms, clinical strategy, and interpretation of disease and literature
• Serve as a core member of the Clinical Matrix Team for assets in development
• Represent Clinical Development on disease area strategy, integrated evidence, and medical affairs strategy teams
• Participate in Oncology Clinical Development-wide initiatives and workstreams as appropriate

Qualifications

• Medical degree with completion of post-medical education residency
• Board/registration in medical oncology, hematology, pathology, or internal medicine
• Oncology experience in pharmaceutical/biotechnology industry and clinical practice in indicated fields
• Documented academic and/or clinical research publication history or clinical practice history in relevant fields
• Strong knowledge of the clinical drug development process and experience in conducting/participating in clinical trials and publications
• Experience in regulatory requirements to support registration and knowledge of GCP

Preferred Qualifications

• Board/registration certified or eligible with a PhD
• Experience leading oncology clinical trials, including study design, data review/interpretation, and overall development process
• Robust knowledge of disease-specific research priorities, public health needs, competitor landscape, and treatment guidelines evolution

Skills

• Strategic collaboration and relationship management with external experts
• Medical monitoring of trials and risk assessment
• Regulatory documentation and cross-functional coordination
• Scientific literature interpretation and data-driven decision making

Education

• Medical degree; residency completed; board/registration in relevant specialty

Additional Requirements

• On-site presence 2‚Äì3 days per week in specified locations (UK, Switzerland, US, or Poland)