Medical Director (Nephrology)

Role Summary

Medical Director to lead and support nephrology clinical programs, with a focus on rare or immune-mediated kidney diseases. This physician-scientist role thrives in a small biotech environment requiring agility, cross-functional collaboration, and scientific leadership. The position contributes to advancing Jade’s pipeline through clinical development and reports to the Executive Medical Director of Clinical Development. Fully remote with some travel.

Responsibilities

• Clinical Development
  • Lead design, execution, and oversight of nephrology clinical trials, including protocol development, study monitoring, and data interpretation.
  • Serve as Medical Monitor for ongoing trials, ensuring patient safety and scientific integrity.
  • Collaborate with clinical operations, regulatory, and biometrics teams to ensure trial success and compliance.
  • Educate and advise clinical sites/investigators to support enrollment and optimal study conduct, including presenting at investigator meetings and site initiation visits, and serving as the medical point of contact for site staff questions about patient eligibility and safety management.
  • Provide medical expertise and support to external partners, vendors, and contractors as required to ensure smooth program execution.
  • Communicate effectively with internal and external stakeholders regarding the assigned clinical program, including the CMO, CEO, external medical experts, and others.

• Regulatory and Scientific Contributions
  • Contribute to regulatory documents (INDs, NDAs, briefing documents, etc.).
  • Support interactions with regulatory authorities and ethics committees.
  • Stay current with scientific literature and competitive landscape in nephrology and related fields.

• Cross-Functional Collaboration
  • Partner with translational science, biomarker, and commercial teams to align clinical strategy with broader company goals.
  • Provide medical input into lifecycle planning and early market preparation.

• Stakeholder Engagement
  • Build relationships with key opinion leaders, investigators, and advocacy groups in nephrology.
  • Represent the company at scientific meetings, advisory boards, and industry events.

• Qualifications
  • MD (or equivalent medical degree); board certification in nephrology strongly preferred.
  • 3+ years of experience as a nephrologist in academia or industry, and/or experience in nephrology clinical trials or rare disease programs.
  • Experience in clinical trial design, execution, and medical monitoring.
  • Strong clinical judgment, scientific rigor, and regulatory knowledge.
  • Ability to work independently and thrive in a fast-paced, matrixed environment.
  • Ability to manage multiple projects simultaneously and prioritize effectively.
  • Strong analytical, problem-solving, and decision-making skills.
  • Excellent communication and interpersonal skills with the ability to influence and motivate cross-functional teams and manage diverse stakeholders.
  • High ethical standards and impeccable integrity; sound judgment with confidential, regulated information.

Additional Requirements

• This is a remote role; periodic travel to scientific conferences, sites, team and company events is required.