Medical Director

Role Summary

Medical Director, Clinical Development is a key clinical leader responsible for the design, execution, and interpretation of clinical trials supporting the development of innovative therapies within Disc's pipeline. Provides strategic and scientific leadership to cross-functional teams, ensuring clinical programs meet regulatory, ethical, and corporate objectives. Supports a clinical-stage program focused on iron metabolism and anemia treatment using a novel, first-in-class negative regulator of hepcidin.

Responsibilities

• Clinical Strategy & Leadership
  • Contribute to the overall clinical development strategy for assigned programs.
  • Define clinical development plans, trial designs, and program milestones in partnership with senior leadership.
  • Provide medical and scientific input into target product profiles, study protocols, investigator brochures, and regulatory documents.
  • Monitor internal and external developments that could impact the development plan and review relevant literature.
  • Evaluate information about diseases and competitive landscape to support development programs and strategic planning.
  • Identify appropriate advisory board experts.
• Clinical Trial Oversight
  • Serve as medical monitor for clinical trials, ensuring subject safety and data integrity.
  • Provide clinical guidance to operational teams, investigators, and external partners.
  • Review and interpret clinical data, prepare clinical study reports, and support publication activities.
  • Oversee clinical content of protocols, INDs, CTAs, investigator brochures, CRFs, annual IND reports, CSRs, and clinical expert reports.
  • Organize and present at clinical advisory boards, DMC, and medical/scientific meetings.
• Cross-Functional Collaboration
  • Collaborate with Clinical Operations, Regulatory Affairs, Biostatistics, Pharmacovigilance, and Medical Affairs to ensure execution of programs.
  • Represent Clinical Development in governance meetings and cross-functional program teams.
  • Support business development and alliance management as needed.
• Regulatory & Compliance
  • Contribute to regulatory submissions (INDs, NDAs, BLAs) and interactions with global health authorities.
  • Ensure compliance with GCP, ICH guidelines, and SOPs.
• Scientific Communication & Leadership
  • Prepare abstracts and manuscripts for publication/presentation.
  • Present clinical data to internal stakeholders, investigators, and at scientific conferences.
  • Mentor junior medical or scientific staff.

Qualifications

• MD with research experience or MD/PhD, fellowship in Hematology/Oncology or related areas, 10‚Äì12 years of related experience.
• Extensive translational or clinical research experience in drug development; biotech/pharma experience preferred.
• Experience developing clinical regulatory strategy.
• Strong academic record with peer-reviewed publications.
• Proven cross-functional collaboration within an organization and with external partners.
• Expertise in data analysis and presentation; knowledge of clinical research methodology, statistics, and interpretation.
• Effective written and oral communication with internal and external stakeholders.
• Experience interacting with management, academicians, clinicians, and scientists; regulatory submissions/interactions with FDA/EMA preferred.
• Ability to travel up to 20% for investigator meetings, regulatory interactions, or conferences.

Skills

• Clinical strategy and leadership
• Medical monitoring of trials
• Regulatory submissions and compliance
• Data analysis and interpretation
• Scientific communication and mentorship

Education

• MD (or equivalent) with relevant subspecialty training; MD/PhD considered.