Medical Director, Clinical Research, Endocrinology
Crinetics Pharmaceuticals
August 29, 2026
Remote friendly (United States)
United States
Clinical Research and Development
Position Summary
The Medical Director, Clinical Sciences will support development and execution of Crinetics’ endocrinology portfolio as part of a multidisciplinary development team.
Essential Job Functions And Responsibilities
- Partner with cross-functional teams to shape and maintain a Clinical Development Plan (CCDP) toward Executive Team approval; contribute to Strategic Plans and the TPP.
- Lead design, planning, and implementation of clinical trials aligned with the CCDP.
- Provide scientific/clinical direction for clinical protocols, amendments, and related documents (e.g., informed consent) with Medical Writing.
- Provide medical monitoring for clinical studies with CRO medical monitors.
- Ensure clinical trials are conducted per GCP and applicable regulatory requirements.
- Provide clinical/scientific input to HEOR-led Patient Reported Outcome research.
- Provide oversight to support enrollment feasibility and protocol-driven eligibility.
- Participate in data analyses and review for CSR completion and filing activities.
- Contribute clinical sections of regulatory documents (e.g., Investigators’ Brochures, briefing books, safety updates, IND/BLA documents, responses to Health Authorities).
- Lead trial-related advisory boards, investigator meetings, and protocol training meetings.
- Collaborate with Medical Affairs and Commercial to optimize study design, execution, reporting, and publication.
- Provide expertise to publications planning and drafting.
- Provide oversight of clinical programs across planning through completion in partnership with Clinical Operations.
- Attend conferences; remain current on therapeutic area information.
- Serve as external clinical face in interactions with development partners and at advisory boards.
- Other duties as assigned.
Education And Experience / Qualifications
- MD with 5+ years clinical research experience (industry or academia); endocrinology subspecialty board certification preferred.
- Equivalent education/experience considered.
- Thorough knowledge of clinical medicine, clinical pharmacology, and related disciplines (e.g., biostatistics, data management, medical writing).
- Deep understanding of strategic and operational clinical research/product development.
- Strong knowledge of FDA/EMA expectations, GCP, ICH guidelines, and clinical drug development.
- Familiarity with FDA/EU agency interactions.
- High-level expertise in day-to-day medical monitoring (eligibility, safety parameters, SAEs and SAE narratives).
- Excellent leadership, interpersonal, and presentation skills; strategic and collaborative.
- Ethical, integrity-focused.
Benefits (as stated)
- Discretionary annual target bonus; stock options; ESPP; 401k match; medical/dental/vision; basic life insurance; 20 days PTO; 10 paid holidays; winter company shutdown.
Travel
- Up to 5%.
The Medical Director, Clinical Sciences will support development and execution of Crinetics’ endocrinology portfolio as part of a multidisciplinary development team.
Essential Job Functions And Responsibilities
- Partner with cross-functional teams to shape and maintain a Clinical Development Plan (CCDP) toward Executive Team approval; contribute to Strategic Plans and the TPP.
- Lead design, planning, and implementation of clinical trials aligned with the CCDP.
- Provide scientific/clinical direction for clinical protocols, amendments, and related documents (e.g., informed consent) with Medical Writing.
- Provide medical monitoring for clinical studies with CRO medical monitors.
- Ensure clinical trials are conducted per GCP and applicable regulatory requirements.
- Provide clinical/scientific input to HEOR-led Patient Reported Outcome research.
- Provide oversight to support enrollment feasibility and protocol-driven eligibility.
- Participate in data analyses and review for CSR completion and filing activities.
- Contribute clinical sections of regulatory documents (e.g., Investigators’ Brochures, briefing books, safety updates, IND/BLA documents, responses to Health Authorities).
- Lead trial-related advisory boards, investigator meetings, and protocol training meetings.
- Collaborate with Medical Affairs and Commercial to optimize study design, execution, reporting, and publication.
- Provide expertise to publications planning and drafting.
- Provide oversight of clinical programs across planning through completion in partnership with Clinical Operations.
- Attend conferences; remain current on therapeutic area information.
- Serve as external clinical face in interactions with development partners and at advisory boards.
- Other duties as assigned.
Education And Experience / Qualifications
- MD with 5+ years clinical research experience (industry or academia); endocrinology subspecialty board certification preferred.
- Equivalent education/experience considered.
- Thorough knowledge of clinical medicine, clinical pharmacology, and related disciplines (e.g., biostatistics, data management, medical writing).
- Deep understanding of strategic and operational clinical research/product development.
- Strong knowledge of FDA/EMA expectations, GCP, ICH guidelines, and clinical drug development.
- Familiarity with FDA/EU agency interactions.
- High-level expertise in day-to-day medical monitoring (eligibility, safety parameters, SAEs and SAE narratives).
- Excellent leadership, interpersonal, and presentation skills; strategic and collaborative.
- Ethical, integrity-focused.
Benefits (as stated)
- Discretionary annual target bonus; stock options; ESPP; 401k match; medical/dental/vision; basic life insurance; 20 days PTO; 10 paid holidays; winter company shutdown.
Travel
- Up to 5%.