Medical Director, Clinical Research, Endocrinology
Crinetics Pharmaceuticals
August 07, 2026
Remote friendly (United States)
United States
Clinical Research and Development
Position Summary
Medical Director, Clinical Sciences will support development and execution of Crinetics’ endocrinology portfolio within a multidisciplinary development team.
Responsibilities
- Partner cross-functionally to shape and maintain a concise Clinical Development Plan (CCDP) toward Executive approval; contribute to Strategic Plans/TPP.
- Lead design, planning, and implementation of clinical trials per the CCDP.
- Provide scientific/clinical direction for protocols (and early CTOs/synopses), amendments, and documents (e.g., informed consent) with Medical Writing.
- Provide medical monitoring with CRO medical monitors; ensure GCP and applicable regulatory compliance.
- Provide scientific input to HEOR-led Patient Reported Outcome research.
- Oversee enrollment feasibility and protocol-driven eligibility.
- Participate in data analyses; support CSR completion and filing activities.
- Contribute to regulatory documents (e.g., Investigators’ Brochures, briefing books, safety updates, IND/BLA materials, responses to Health Authorities).
- Lead advisory boards, investigator meetings, and protocol training.
- Collaborate with Medical Affairs/Commercial to optimize clinical design, execution, reporting, and publication.
- Provide publication expertise; oversee clinical program planning through completion.
- Attend conferences; act as external clinical “face” as needed.
Qualifications
- MD with 5+ years clinical research experience (industry or academia); endocrinology subspecialty board certification preferred.
- Strong knowledge of clinical medicine/pharmacology and related disciplines (biostatistics, data management, medical writing).
- Deep understanding of clinical research/product development strategy and operations.
- Solid knowledge of FDA/EMA, GCP, ICH, and clinical drug development.
- Familiarity with FDA/EU regulatory agency interactions.
- High-level expertise in day-to-day medical monitoring (eligibility, safety review, SAEs).
- Leadership, collaboration/influencing, presentation skills; ethical/integrity.
Benefits (as stated)
Discretionary annual target bonus, stock options, ESPP, 401k match; medical/dental/vision/basic life; 20 days PTO, 10 paid holidays, winter company shutdown.
Medical Director, Clinical Sciences will support development and execution of Crinetics’ endocrinology portfolio within a multidisciplinary development team.
Responsibilities
- Partner cross-functionally to shape and maintain a concise Clinical Development Plan (CCDP) toward Executive approval; contribute to Strategic Plans/TPP.
- Lead design, planning, and implementation of clinical trials per the CCDP.
- Provide scientific/clinical direction for protocols (and early CTOs/synopses), amendments, and documents (e.g., informed consent) with Medical Writing.
- Provide medical monitoring with CRO medical monitors; ensure GCP and applicable regulatory compliance.
- Provide scientific input to HEOR-led Patient Reported Outcome research.
- Oversee enrollment feasibility and protocol-driven eligibility.
- Participate in data analyses; support CSR completion and filing activities.
- Contribute to regulatory documents (e.g., Investigators’ Brochures, briefing books, safety updates, IND/BLA materials, responses to Health Authorities).
- Lead advisory boards, investigator meetings, and protocol training.
- Collaborate with Medical Affairs/Commercial to optimize clinical design, execution, reporting, and publication.
- Provide publication expertise; oversee clinical program planning through completion.
- Attend conferences; act as external clinical “face” as needed.
Qualifications
- MD with 5+ years clinical research experience (industry or academia); endocrinology subspecialty board certification preferred.
- Strong knowledge of clinical medicine/pharmacology and related disciplines (biostatistics, data management, medical writing).
- Deep understanding of clinical research/product development strategy and operations.
- Solid knowledge of FDA/EMA, GCP, ICH, and clinical drug development.
- Familiarity with FDA/EU regulatory agency interactions.
- High-level expertise in day-to-day medical monitoring (eligibility, safety review, SAEs).
- Leadership, collaboration/influencing, presentation skills; ethical/integrity.
Benefits (as stated)
Discretionary annual target bonus, stock options, ESPP, 401k match; medical/dental/vision/basic life; 20 days PTO, 10 paid holidays, winter company shutdown.