Medical Director, Clinical Development
Verastem Oncology
August 14, 2026
Remote friendly (Greater Boston)
United States
Clinical Research and Development
Summary: Medical Director (level dependent on qualifications) reporting to the VP of Clinical Development. Provides medical and scientific leadership for the VS-7375 (KRAS G12D ON/OFF inhibitor) program.
Responsibilities
- Support design and execution of assigned clinical trial(s) with cross-functional teams.
- Serve as primary medical/safety contact for assigned trials; be primary contact for medical inquiries from investigators and regulatory agencies; ensure consistent protocol interpretation.
- Partner with Clinical Science, Data Management, and Statistical Programming to ensure data integrity; lead data reviews and insight generation.
- Collaborate with Safety on reporting AEs/SAEs; contribute to safety profile characterization and risk mitigation.
- Integrate preclinical, pharmacology, translational science, and clinical data to generate actionable development insights; assess benefit-risk.
- Author key study/regulatory documents (protocol, investigator brochure, informed consent, clinical study reports) and contribute to publications.
- Represent the program with internal/external stakeholders; lead and present at investigator meetings and advisory committees.
- Maintain oncology scientific/clinical knowledge and provide input on pipeline and translational/preclinical work.
Required qualifications
- M.D. (or equivalent).
- 3+ years biotech/pharma oncology drug development (or substantial clinical investigator experience).
- cGCP knowledge; clinical trial design and global drug development understanding.
- Knowledge of regulatory environment (e.g., FDA/EMA).
- Independent judgment, strong communication/influencing, relationship-building, analytical/presentation skills.
- Ability to travel up to 20%.
Preferred qualifications
- Board-certified in oncology; early phase development experience; working knowledge of translational science.
Compensation/benefits
- Base salary range: $250,000–$310,000; eligible for annual bonus, equity, and competitive benefits package.
Responsibilities
- Support design and execution of assigned clinical trial(s) with cross-functional teams.
- Serve as primary medical/safety contact for assigned trials; be primary contact for medical inquiries from investigators and regulatory agencies; ensure consistent protocol interpretation.
- Partner with Clinical Science, Data Management, and Statistical Programming to ensure data integrity; lead data reviews and insight generation.
- Collaborate with Safety on reporting AEs/SAEs; contribute to safety profile characterization and risk mitigation.
- Integrate preclinical, pharmacology, translational science, and clinical data to generate actionable development insights; assess benefit-risk.
- Author key study/regulatory documents (protocol, investigator brochure, informed consent, clinical study reports) and contribute to publications.
- Represent the program with internal/external stakeholders; lead and present at investigator meetings and advisory committees.
- Maintain oncology scientific/clinical knowledge and provide input on pipeline and translational/preclinical work.
Required qualifications
- M.D. (or equivalent).
- 3+ years biotech/pharma oncology drug development (or substantial clinical investigator experience).
- cGCP knowledge; clinical trial design and global drug development understanding.
- Knowledge of regulatory environment (e.g., FDA/EMA).
- Independent judgment, strong communication/influencing, relationship-building, analytical/presentation skills.
- Ability to travel up to 20%.
Preferred qualifications
- Board-certified in oncology; early phase development experience; working knowledge of translational science.
Compensation/benefits
- Base salary range: $250,000–$310,000; eligible for annual bonus, equity, and competitive benefits package.