Medical Director, Cardiovascular

Role: Medical Director, Cardiovascular at MannKind, providing strategic scientific leadership in heart failure and fluid overload therapies within the company’s cardiometabolic and orphan lung disease focus. Responsibilities include leading clinical development strategies for cardiorenal disorders, overseeing Phase 1–4 trial design and execution, and integrating biomarker, safety, translational medicine, and regulatory aspects to support pipeline advancement. The role involves cross-functional collaboration with Clinical Development, Medical Affairs, Regulatory, and Commercial teams to shape evidence strategies, ensure regulatory compliance, and support market access efforts. Key tasks encompass clinical protocol development, trial oversight, safety monitoring, and regulatory submissions, with an emphasis on high-quality data generation aligned with GxP standards. The Medical Director also provides scientific input on evidence generation, guides publications and scientific communication, and contributes to enterprise governance and portfolio decisions. Leadership responsibilities include mentoring medical staff, contributing to organizational development, and serving on senior leadership teams. Qualifications require an M.D. (preferably with experience as a cardiologist or nephrologist) and 5+ years in medical affairs or clinical development within biotech/pharma, with expertise in cardiovascular disease, clinical trial design, and regulatory processes. The role demands strong scientific communication, leadership, and collaboration skills, with approximately 20% travel. High-value biopharma specifics include focus on chronic cardiovascular and renal diseases, clinical trial oversight, biomarker strategy, regulatory engagement, and cross-functional leadership within a biotech setting.