Market Transformation Manager

Job Description Job Title: Manager, Market Transformation Company Overview: At Vertex Pharmaceuticals, we are committed to transforming the lives of people with serious diseases. Our innovative approach to research and development has led to groundbreaking advancements in healthcare, including the development of new treatments for pain management, cystic fibrosis, and other critical conditions. We are dedicated to fostering a vibrant, inclusive culture that empowers our employees to make a meaningful impact on patients’ lives. Role Summary: Vertex Pharmaceuticals is seeking a dynamic and strategic Manager of Market Transformation to join our US Market Transformation team. This role will focus on identifying, evaluating, and managing strategic projects that align with our business priorities, particularly as we prepare for the commercialization of an investigational acute pain product. The Manager of Market Transformation will play a pivotal role in shaping and executing strategies, driving innovation, and collaborating across multiple teams to ensure the successful implementation of market transformation initiatives. Key Responsibilities: Collaborate with the Head of Market Transformation to define the vision, objectives, and strategic direction of the Market Transformation team. Conduct market research, analyze syndicated data, and engage with external stakeholders to identify and catalog strategic opportunities. Develop clear problem and challenge statements to guide internal stakeholders in conceptualizing opportunities. Create and implement an end-to-end framework for managing opportunities, including business case development, decision-making processes, and governance. Define and track key performance indicators (KPIs) to measure the success and operational efficiency of projects. Partner with cross-functional teams, including Market Access, Strategic Accounts, Commercial, Marketing, Contracting, Trade, Pricing, Legal, Compliance, and Leadership, to execute strategic projects. Lead change management initiatives, focusing on customer-centered design thinking, idea generation, and adaptability. Support the development and scaling of innovative programs, partnerships, and new capabilities aligned with business unit and enterprise priorities. Ensure alignment with organizational goals and compliance with legal, regulatory, and policy requirements. Required Qualifications: Bachelor’s degree in a relevant field. A minimum of 4-5 years of experience in healthcare or biopharmaceuticals, with a background in marketing, consulting, or agency roles. Proven ability to define and execute strategies, with a track record of driving innovative approaches to maximize effectiveness. Strong understanding of legal, regulatory, and compliance requirements for pre- and post-approval activities. Analytical mindset with the ability to generate insights and apply them to business opportunities. Exceptional written and verbal communication skills, including executive presence. Proficiency in Microsoft Office Suite. Technical Skills Required: Expertise in market research and data analysis. Proficiency in developing business cases and decision-making frameworks. Experience with customer-centered design thinking and change management. Familiarity with digital health, AI, and Health Information Technology (HIT) solutions. Ability to track and analyze market, policy, and competitive trends. Preferred Skills: Entrepreneurial mindset with the ability to challenge the status quo. Experience in developing and managing partnerships and alliances. Knowledge of emerging trends in healthcare and biopharmaceuticals. Experience in scaling innovative programs across therapeutic areas. Benefits: Competitive salary and performance-based bonuses. Comprehensive health, dental, and vision insurance. 401(k) retirement savings plan with company match. Generous paid time off and holiday schedule. Professional development opportunities. Inclusive and diverse workplace culture. Join Vertex Pharmaceuticals and be part of a team that is transforming the future of healthcare. Together, we can make a difference in the lives of patients. Pay Range: $120,000 - $180,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.