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Manager, Supply Chain Planning

Denali Therapeutics
August 31, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Operations
Role: Clinical Supply Chain Planner responsible for leading demand forecasting, supply planning, and inventory management for Denali's neurodegenerative disease programs. Objectives include ensuring uninterrupted GMP material supply, developing supply chain strategies, and supporting program development. Responsibilities encompass executing scenario planning, managing stakeholder communications, troubleshooting issues, and driving operational improvements across CMC, Manufacturing, QA, Regulatory, Clinical Operations, and Finance functions. Requirements: Bachelor’s degree in Life Sciences, Engineering, Operations, or related field, with 8+ years of experience including 3+ years in clinical supply chain planning within the Life Sciences. Skills include influence management, cross-functional collaboration, project prioritization, and communication. Preferred: experience leading process improvements and working knowledge of cGMP and FDA regulations. High-Value: focus on neurodegenerative diseases, clinical-stage programs, GMP supply chain, and cross-functional interface with development and manufacturing teams. WorkSetup: not specified; likely hybrid or onsite due to cross-departmental coordination.