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Manager, SOX Compliance

MBX Biosciences, Inc.
June 26, 2026
Remote friendly (Carmel, IN)
United States
Corporate Functions
Position Summary
We are seeking a Manager, SOX Compliance and Accounting to oversee Sarbanes-Oxley (SOX) compliance and project accounting.

Key Responsibilities
- Manage the buildout of the Company’s SOX Compliance program, including entity-level controls, process-level controls, and ITGCs.
- Conduct ongoing risk and control assessments (financial reporting risks, entity- and process-level controls, IT general and application controls).
- Lead internal controls walkthroughs and testing.
- Maintain and improve SOX documentation (risk control matrices, process flows, test procedures).
- Coordinate with the external audit team related to SOX compliance.
- Recommend and implement changes to strengthen internal controls and financial processes.
- Support major project accounting (percentage of completion entries) and standardize related processes.
- Assist with accounting functions and month-end closing to ensure GAAP compliance, internal controls, and timely completion.
- Assist with preparation and coordination of internal/external annual audits and quarterly reviews.
- Provide support for special projects and ad-hoc reporting/analysis.

Education & Qualifications
- Degree in Finance or Accounting (Master’s/MBA a plus).
- Corporate accounting experience in life sciences or CPA with audit experience (life science clients a plus) required.
- Technical knowledge of US GAAP and the COSO internal control framework.

Experience & Additional Skills
- 3+ years in financial reporting, audit, or accounting.
- 2+ years of SOX, internal controls, or audit experience.
- Ability to design and maintain internal controls and SOX.
- Strong documentation skills; ability to coordinate with auditors and process owners.
- Ability to oversee/assist month-end accounting processes.
- Assist with SEC filings preparation as needed (10-Q, 10-K, 8-K, Forms 3/4, proxy statements, earnings releases) ensuring US GAAP and SEC compliance.
- Proficiency in Microsoft Office Suite; ActiveDisclosure and NetSuite ERP a plus.