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Manager, CMC Project Management

Alnylam Pharmaceuticals
September 15, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Operations
Role: Project Manager for CMC development programs within Technical Operations and Quality at Alnylam, primarily supporting RNAi therapeutics. Responsibilities: lead cross-functional project execution, develop integrated plans, manage risks and dependencies, facilitate team meetings, and drive process improvements. Coordinates with Manufacturing, Process Sciences, Analytical Science, Supply Chain, Quality, and Regulatory teams, as well as external partners, to ensure timely delivery of preclinical to commercial CMC milestones. Qualifications: Bachelor's degree or equivalent; minimum 5 years' project management experience in biotech or pharma, supporting CMC programs (preclinical through commercial). Skills include strong organizational, analytical, communication, and stakeholder management, with proficiency in project management tools like Smartsheet, Planisware, or MS Project. High-Value: CMC development, RNAi therapeutics, biotech/pharma industry, cross-functional leadership, risk management, process improvement. Work Setup: hybrid in Cambridge, MA.