Internal Audit Manager
Vertex Pharmaceuticals
June 27, 2026
Remote friendly (Boston, MA)
United States
Corporate Functions
General Summary:
Through internal audits, the Internal Audit Manager will identify risk areas, evaluate business process controls, and complete test plans on operational audits. Provide recommendations to improve the effectiveness and efficiency of operations and business systems. Support the yearly internal control review by interacting with SOX testers, stakeholders, and subject matter experts on special projects and departmental goal development/execution.
Key Duties And Responsibilities:
- Plan and perform financial, operational, and as applicable, IT audits; ensure end-to-end execution and compliance with reporting policies/procedures.
- Apply financial/quantitative analyses and risk assessment; document findings/work papers.
- Maintain knowledge of generally accepted accounting principles/standards and/or IT frameworks.
- Communicate audit results, control weaknesses, deficiencies, risks, and opportunities to management.
- Review, appraise, and test internal controls for Sarbanes-Oxley Act compliance.
- Collaborate with audit team members and business stakeholders, including multicultural/global teams.
- Coordinate with the Engagement Director; incorporate feedback and adjust approach.
- Present findings, conclusions, and recommended actions to business management.
Knowledge And Skills:
- Experience in Life Sciences or related sector.
- Strong organizational/project management; written/verbal communication.
- Detail-oriented; multitask and meet deadlines; collaborate with diverse teams.
- Knowledge of audit methodology, risk assessment, internal control concepts.
- Ability to analyze workflows, identify gaps/bottlenecks.
- Data analytics; SOC1 reviews; understanding ITGCs.
- Ability to train audit staff and operate independently in multi-location environments.
- CPA, CIA, or CISA (or equivalent).
Education And Experience:
- Bachelor’s degree in accounting/finance/information systems or related field.
- Typically 5+ years auditing experience (Big 4 strongly preferred).
Application Instructions:
Contact Talent Acquisition at ApplicationAssistance@vrtx.com for accommodation requests in connection with the hiring process.
Through internal audits, the Internal Audit Manager will identify risk areas, evaluate business process controls, and complete test plans on operational audits. Provide recommendations to improve the effectiveness and efficiency of operations and business systems. Support the yearly internal control review by interacting with SOX testers, stakeholders, and subject matter experts on special projects and departmental goal development/execution.
Key Duties And Responsibilities:
- Plan and perform financial, operational, and as applicable, IT audits; ensure end-to-end execution and compliance with reporting policies/procedures.
- Apply financial/quantitative analyses and risk assessment; document findings/work papers.
- Maintain knowledge of generally accepted accounting principles/standards and/or IT frameworks.
- Communicate audit results, control weaknesses, deficiencies, risks, and opportunities to management.
- Review, appraise, and test internal controls for Sarbanes-Oxley Act compliance.
- Collaborate with audit team members and business stakeholders, including multicultural/global teams.
- Coordinate with the Engagement Director; incorporate feedback and adjust approach.
- Present findings, conclusions, and recommended actions to business management.
Knowledge And Skills:
- Experience in Life Sciences or related sector.
- Strong organizational/project management; written/verbal communication.
- Detail-oriented; multitask and meet deadlines; collaborate with diverse teams.
- Knowledge of audit methodology, risk assessment, internal control concepts.
- Ability to analyze workflows, identify gaps/bottlenecks.
- Data analytics; SOC1 reviews; understanding ITGCs.
- Ability to train audit staff and operate independently in multi-location environments.
- CPA, CIA, or CISA (or equivalent).
Education And Experience:
- Bachelor’s degree in accounting/finance/information systems or related field.
- Typically 5+ years auditing experience (Big 4 strongly preferred).
Application Instructions:
Contact Talent Acquisition at ApplicationAssistance@vrtx.com for accommodation requests in connection with the hiring process.