Innovation & Business Transformation, Sr. Manager
Vertex Pharmaceuticals Incorporated
October 15, 2026
Full-time
Remote friendly (Boston, MA)
United States
IT
Job Description
General Summary:
The Senior Manager, Innovation and Business Transformation drives the execution of defined technology-enabled transformation initiatives across Medical Writing Science (MWS). The role assesses business needs and workflows, translates requirements into practical implementation plans, coordinates testing and implementation activities, and enables successful adoption and continuous improvement of new capabilities. Working closely with MWS leaders, users, and enterprise technology partners, the Senior Manager ensures solutions address established business needs, are effectively implemented, and improve scientific and operational ways of working.
Key Duties and Responsibilities:
Execute defined technology-enabled transformation initiatives, coordinating activities, milestones, stakeholders, and deliverables to achieve established business outcomes.
Assess current-state workflows, identify pain points and user needs, and contribute to future-state process design and improvement recommendations.
Translate business needs into detailed requirements, process maps, user stories, acceptance criteria, workflow specifications, implementation plans, and success measures.
Partner with MWS subject matter experts, users, and enterprise technology teams to validate workflows and requirements and support delivery of fit-for-purpose solutions.
Evaluate proposed capabilities against defined business requirements, workflow fit, usability, quality, risk, and expected outcomes, providing recommendations to initiative leaders.
Plan and facilitate prototypes, pilots, workflow validation, user acceptance testing, and implementation activities, documenting outcomes and coordinating resolution of identified issues.
Execute organizational readiness and change activities for assigned initiatives, including impact assessment, stakeholder engagement, communications, training, user support, and adoption.
Monitor adoption, user feedback, process performance, and initiative outcomes using appropriate reporting and enablement tools; identify improvement opportunities and support optimization and sustained use.
Coordinate project stakeholders and activities, manage delivery risks and dependencies within assigned work, and escalate significant decisions, risks, and trade-offs to initiative leadership.
Knowledge and Skills:
Experience supporting business transformation, digital innovation, AI enablement, process improvement, automation, analytics, or technology-enabled workflow initiatives.
Demonstrated ability to translate business and user needs into requirements, process maps, user stories, acceptance criteria, implementation plans, and success measures.
Ability to analyze current-state workflows, identify pain points, and contribute to practical future-state process improvements.
Working knowledge of AI-enabled capabilities, digital platforms, automation, analytics, and emerging technologies and their potential application to scientific and operational workflows.
Experience supporting or facilitating prototypes, pilots, user acceptance testing, workflow validation, implementation, and post-implementation improvement.
Experience supporting change and adoption activities, including stakeholder engagement, communications, training, user feedback, and adoption monitoring.
Strong analytical, project management, facilitation, and problem-solving skills, with the ability to manage activities, dependencies, risks, and competing priorities.
Strong communication and collaboration skills, with the ability to work effectively across scientific, business, user, technology, and governance stakeholders.
Education and Experience:
6 years of experience working in the biotechnology or pharmaceutical industry, or in a relevant technology, engineering business field, or the equivalent combination of education and experience.
Bachelor's degree in technology discipline or equivalent
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$134,200 - $201,200
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid : work remotely up to two days per week; or select
2. On-Site : work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
General Summary:
The Senior Manager, Innovation and Business Transformation drives the execution of defined technology-enabled transformation initiatives across Medical Writing Science (MWS). The role assesses business needs and workflows, translates requirements into practical implementation plans, coordinates testing and implementation activities, and enables successful adoption and continuous improvement of new capabilities. Working closely with MWS leaders, users, and enterprise technology partners, the Senior Manager ensures solutions address established business needs, are effectively implemented, and improve scientific and operational ways of working.
Key Duties and Responsibilities:
Execute defined technology-enabled transformation initiatives, coordinating activities, milestones, stakeholders, and deliverables to achieve established business outcomes.
Assess current-state workflows, identify pain points and user needs, and contribute to future-state process design and improvement recommendations.
Translate business needs into detailed requirements, process maps, user stories, acceptance criteria, workflow specifications, implementation plans, and success measures.
Partner with MWS subject matter experts, users, and enterprise technology teams to validate workflows and requirements and support delivery of fit-for-purpose solutions.
Evaluate proposed capabilities against defined business requirements, workflow fit, usability, quality, risk, and expected outcomes, providing recommendations to initiative leaders.
Plan and facilitate prototypes, pilots, workflow validation, user acceptance testing, and implementation activities, documenting outcomes and coordinating resolution of identified issues.
Execute organizational readiness and change activities for assigned initiatives, including impact assessment, stakeholder engagement, communications, training, user support, and adoption.
Monitor adoption, user feedback, process performance, and initiative outcomes using appropriate reporting and enablement tools; identify improvement opportunities and support optimization and sustained use.
Coordinate project stakeholders and activities, manage delivery risks and dependencies within assigned work, and escalate significant decisions, risks, and trade-offs to initiative leadership.
Knowledge and Skills:
Experience supporting business transformation, digital innovation, AI enablement, process improvement, automation, analytics, or technology-enabled workflow initiatives.
Demonstrated ability to translate business and user needs into requirements, process maps, user stories, acceptance criteria, implementation plans, and success measures.
Ability to analyze current-state workflows, identify pain points, and contribute to practical future-state process improvements.
Working knowledge of AI-enabled capabilities, digital platforms, automation, analytics, and emerging technologies and their potential application to scientific and operational workflows.
Experience supporting or facilitating prototypes, pilots, user acceptance testing, workflow validation, implementation, and post-implementation improvement.
Experience supporting change and adoption activities, including stakeholder engagement, communications, training, user feedback, and adoption monitoring.
Strong analytical, project management, facilitation, and problem-solving skills, with the ability to manage activities, dependencies, risks, and competing priorities.
Strong communication and collaboration skills, with the ability to work effectively across scientific, business, user, technology, and governance stakeholders.
Education and Experience:
6 years of experience working in the biotechnology or pharmaceutical industry, or in a relevant technology, engineering business field, or the equivalent combination of education and experience.
Bachelor's degree in technology discipline or equivalent
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$134,200 - $201,200
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid : work remotely up to two days per week; or select
2. On-Site : work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com