Role Summary
In Vivo Biologist- Immunology will develop and validate disease models of inflammation and autoimmunity to interrogate novel therapeutics within Lilly Immunology Discovery. The role is part of the immunology in vivo pharmacology group, located at the Lilly Biotechnology Center in San Diego, with projects supported in San Diego, Boston, and the Corporate Center in Indianapolis. The candidate will conduct in vivo efficacy studies, perform in vitro assays on study tissue samples, and collaborate with immunology and cross-functional teams.
Responsibilities
- Perform all aspects of in vivo experiments: dose formulation, animal handling, dosing (PO, IP, SC, ID, IV), blood collection, small animal surgery, and tissue collection/processing and planning within the pharmacology team.
- Analyze and graph data for review.
- Perform ELISAs (or similar platform) on study samples.
- Organize data and present findings at team meetings.
Qualifications
- Required: BS or MS in physiology, biology, pharmacology or closely related field with 2+ years of in vivo experience.
Skills
- Skilled in dose formulation, animal handling, blood collection, animal surgery, and tissue collection/processing.
- Experienced using Excel and GraphPad Prism for analysis and statistics.
- Diligent record keeping; ability to design, analyze, and interpret study results; good organizational and communication skills with the ability to present results in internal meetings.
- Knowledge of molecular biology (e.g., RNA isolation, RT-PCR).
- Familiarity with imaging processes (IHC/IF, IVIS, Phenocycler), FACS analysis and FloJo, and/or cell culture techniques a plus.
Education
- BS or MS in physiology, biology, pharmacology or closely related field.
Additional Requirements
- This position will require occasional weekend work.