Immunology Senior Research Scientist - Spatial Transcriptomics

Role: Senior Scientist, Spatial Transcriptomics at Vertex, focused on advancing spatial biology research to elucidate disease mechanisms and therapeutic responses. Responsibilities include designing and executing spatial transcriptomics studies, characterizing tissue architecture and cell interactions, integrating multi-omics datasets, and developing workflows. The role involves collaborative engagement with cross-functional teams spanning disease biology, pharmacology, and bioinformatics to incorporate spatial insights into drug discovery and biomarker development. Requirements: PhD in a relevant biomedical science with 2+ years of experience or equivalent, expertise in spatial transcriptomics, tissue-based molecular profiling, assay development, and data analysis using R/Python. Preferred skills include hands-on experience with platforms like 10x Genomics Visium or Nanostring CosMx, knowledge of histology and multiplexed tissue profiling, and prior support of translational or biomarker programs, especially in immunology or inflammation. The position emphasizes technical innovation, data quality, and reproducibility. It is an on-site role requiring five days weekly with flexible elements. The role offers competitive salary ($124,200 - $186,400), bonuses, and benefits, within a high-value biopharma setting focused on serious diseases. High-value specifics: spatial transcriptomics, tissue architecture, cell interactions, multi-modal data integration, immunology, inflammation, drug discovery, translational research.