Health Economics & Outcomes Research Associate Director, Pain
Vertex Pharmaceuticals
June 27, 2026
Remote friendly (Boston, MA)
United States
Market Access
General Summary:
- The Health Economics & Outcomes Research Associate Director will lead the development and execution of health economics and outcomes research studies in support of Vertex products. Reports to the Director, HEOR Pain.
Key Duties and Responsibilities:
- Lead others to execute complex HEOR evidence generation, including cost-effective analysis and budget impact models; prospective and retrospective observational studies; ITCs; meta-analyses and systematic reviews; patient-reported outcomes measure development and validation; and other research as needed to support asset value.
- Gather and synthesize insights from payers, KOLs, and HEOR experts; stay current with scientific and policy trends and best practices; apply strategic and content expertise to strategy planning.
- Apply best practices to provide key input to the design of Vertex observational research studies.
- Collaborate with medical communications teams on publication strategy; ensure timely dissemination of HEOR evidence with maximum impact.
- Partner with Global Pricing and Market Access to support production of GVD and Value Narrative.
Knowledge and Skills:
- Strong publication track record in peer-reviewed journals.
- Technical expertise in HEOR; ability to formulate and lead creative, technically/scientifically rigorous research aligned with best HEOR practices.
- Strong verbal and written communication skills, including presenting and persuading across varied audiences.
- Ability to apply knowledge of the US healthcare system, global health technology appraisal requirements, and clinical development to identify evidence gaps and develop evidence-generation strategies.
- Understanding of the pharmaceutical industry legal/regulatory environment; strong compliance and ethical conduct.
Education and Experience:
- Advanced degree (PhD, MD, Master’s, MPH, or PharmD) in a relevant discipline.
- Typically 8 years of experience with substantial HEOR background (or equivalent combination of education and experience).
Pay/Benefits:
- Annual bonus and annual equity awards.
- Total Rewards benefits include medical, dental, vision; paid time off (including a week-long company shutdown in the Summer and the Winter); educational assistance including student loan repayment; commuting subsidy; matching charitable donations; 401(k).
Flex Designation:
- Hybrid: work remotely up to two days per week; or On-Site: work five days per week on-site with ad hoc flexibility.
- The Health Economics & Outcomes Research Associate Director will lead the development and execution of health economics and outcomes research studies in support of Vertex products. Reports to the Director, HEOR Pain.
Key Duties and Responsibilities:
- Lead others to execute complex HEOR evidence generation, including cost-effective analysis and budget impact models; prospective and retrospective observational studies; ITCs; meta-analyses and systematic reviews; patient-reported outcomes measure development and validation; and other research as needed to support asset value.
- Gather and synthesize insights from payers, KOLs, and HEOR experts; stay current with scientific and policy trends and best practices; apply strategic and content expertise to strategy planning.
- Apply best practices to provide key input to the design of Vertex observational research studies.
- Collaborate with medical communications teams on publication strategy; ensure timely dissemination of HEOR evidence with maximum impact.
- Partner with Global Pricing and Market Access to support production of GVD and Value Narrative.
Knowledge and Skills:
- Strong publication track record in peer-reviewed journals.
- Technical expertise in HEOR; ability to formulate and lead creative, technically/scientifically rigorous research aligned with best HEOR practices.
- Strong verbal and written communication skills, including presenting and persuading across varied audiences.
- Ability to apply knowledge of the US healthcare system, global health technology appraisal requirements, and clinical development to identify evidence gaps and develop evidence-generation strategies.
- Understanding of the pharmaceutical industry legal/regulatory environment; strong compliance and ethical conduct.
Education and Experience:
- Advanced degree (PhD, MD, Master’s, MPH, or PharmD) in a relevant discipline.
- Typically 8 years of experience with substantial HEOR background (or equivalent combination of education and experience).
Pay/Benefits:
- Annual bonus and annual equity awards.
- Total Rewards benefits include medical, dental, vision; paid time off (including a week-long company shutdown in the Summer and the Winter); educational assistance including student loan repayment; commuting subsidy; matching charitable donations; 401(k).
Flex Designation:
- Hybrid: work remotely up to two days per week; or On-Site: work five days per week on-site with ad hoc flexibility.