Health Economics & Outcomes Research Associate Director (HYBRID)

Role Summary

Health Economics & Outcomes Research Associate Director (HYBRID) at Vertex. Leads HEOR strategy development and execution to optimize value propositions for CF and early pipeline assets across development stages, including launch and post-launch, reporting to the Senior Director HEOR, CF and Early Pipeline.

Responsibilities

• Leads execution of complex HEOR evidence generation studies, including prospective and retrospective observational studies, systematic literature reviews, cost-effectiveness analyses and budget impact models, indirect treatment comparisons, COA strategy, PRO measure development and validation, as needed, to support asset value
• Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; accountable for study design, data analysis and the quality of the evidence produced; strong project management to ensure studies are delivered on time and within budget
• Collaborates with the medical communications teams on publication strategy and ensures dissemination of HEOR evidence is timely and impactful
• Partners and works closely with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier)

Qualifications

• Strong track record of publication in peer-reviewed journals
• Strong background in clinical outcome assessment (COA) measurement strategy; experience in PRO development/validation and qualitative research methodology
• Technical expertise in HEOR; ability to formulate and lead creative research projects with rigorous conduct following best HEOR practices
• Strong verbal and written communications skills, including presentation skills; ability to communicate complex concepts to diverse audiences
• Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development to identify evidence gaps and formulate strategies
• Understanding of the legal and regulatory environment of the pharmaceutical industry, with a compliant and ethical work history

Education

• Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline
• Typically requires 8 years of experience, with substantial HEOR background, or an equivalent combination of education and experience