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Head of R&D Portfolio & Project Management

Illumina
September 04, 2026
Full-time
Remote friendly (San Diego, CA)
Worldwide
Operations
Role: Head of R&D Portfolio & Project Management Office at Illumina, responsible for driving execution excellence across complex R&D initiatives. Objectives include ensuring predictable delivery, operational discipline, and continuous process improvement of portfolio, program, and project management systems. Responsibilities encompass leading a global PMO, designing scalable practices, translating portfolio priorities into actionable plans, and integrating AI to enhance efficiency. This role also partners with R&D Strategy & Portfolio, manages governance, and provides insights for decision-making, while developing high-performing talent and fostering an inclusive culture. Requirements: 12-15+ years in R&D portfolio/project management, with a strong track record in building PMO capabilities, delivering cross-product development programs, and leading change. An advanced degree in Life Sciences, Business, or related fields (MBA or PhD preferred), PMP or similar certification preferred. High-Value: experience in managing complex R&D portfolios within biotech, diagnostics, or genomics sectors; proficiency in stage-gate processes, risk management, and data-driven decision-making; and experience with cross-functional stakeholder engagement in matrixed organizations. Work setup: Not specified, but likely hybrid or flexible based on global scope.