Head of Neuromuscular Diseases, Translational Medicine
Novartis
3 months ago
Remote friendly (San Diego, CA)
United States
$288,400 - $535,600 USD yearly
Clinical Research and Development
Strategic Leadership & Scientific Direction
- Define and oversee the long-term translational strategy for the Neuromuscular Pillar, ensuring scientific excellence and alignment with broader BR and TM priorities.
- Serve as a senior advisor/thought leader in neuromuscular disorders to inform program design, biomarker strategy, and patient-relevant endpoints.
Program & Portfolio Leadership
- Lead global translational teams across Phase I–IIa (“Discovery” through TDP), driving high-quality development strategies in one or multiple neuromuscular indications.
- Represent TM on global program teams (GPT) and decision boards to ensure neuromuscular programs meet quality, regulatory, and differentiation objectives.
Translational & Clinical Development Excellence
- Lead the design and execution of First-in-Human (FIH) and Phase IIa studies with clinical, regulatory, biomarker, and profiling partners.
- Create clinical components of key documents (e.g., Clinical Trial Protocols, Investigator’s Brochures, Clinical Study Reports, and regulatory documents) with high quality and consistency.
Leadership of People, Culture, and Matrix Teams
- Champion empowerment, innovation, and collaboration across TM and broader BR organizations.
- Mentor and develop scientific talent across translational and clinical functions.
External Impact & Partnerships
- Lead interactions with external stakeholders (e.g., regulators, KOLs, data monitoring committees, advisory boards) and internal NVS stakeholders.
- Contribute to opportunity assessments and due diligence for neuromuscular and adjacent therapeutic areas.
Essential Requirements
- MD and PhD required with clinical subspecialty training in neurological diseases; deep expertise in neuromuscular disorders and gene therapies.
- 10–15+ years of experience in translational medicine, early clinical development, or experimental therapeutics.
- Proven success leading complex global programs and cross-functional scientific teams.
- Ability to shape development strategies, execute early clinical studies, and influence regulatory packages supporting differentiation.
- Experience in a pharmaceutical/biotech company strongly preferred.
Desirable Requirements
- Direct people management experience.
Benefits (explicitly stated)
- Performance-based cash incentive; eligibility for annual equity awards (level-dependent).
- US-based benefits: health, life and disability; 401(k) with company contribution and match; other benefits; generous time off (vacation, personal days, holidays, and other leaves).
Application instructions
- For reasonable accommodations: e-mail [email protected] or call +1(877)395-2339; include the job requisition number.
- Define and oversee the long-term translational strategy for the Neuromuscular Pillar, ensuring scientific excellence and alignment with broader BR and TM priorities.
- Serve as a senior advisor/thought leader in neuromuscular disorders to inform program design, biomarker strategy, and patient-relevant endpoints.
Program & Portfolio Leadership
- Lead global translational teams across Phase I–IIa (“Discovery” through TDP), driving high-quality development strategies in one or multiple neuromuscular indications.
- Represent TM on global program teams (GPT) and decision boards to ensure neuromuscular programs meet quality, regulatory, and differentiation objectives.
Translational & Clinical Development Excellence
- Lead the design and execution of First-in-Human (FIH) and Phase IIa studies with clinical, regulatory, biomarker, and profiling partners.
- Create clinical components of key documents (e.g., Clinical Trial Protocols, Investigator’s Brochures, Clinical Study Reports, and regulatory documents) with high quality and consistency.
Leadership of People, Culture, and Matrix Teams
- Champion empowerment, innovation, and collaboration across TM and broader BR organizations.
- Mentor and develop scientific talent across translational and clinical functions.
External Impact & Partnerships
- Lead interactions with external stakeholders (e.g., regulators, KOLs, data monitoring committees, advisory boards) and internal NVS stakeholders.
- Contribute to opportunity assessments and due diligence for neuromuscular and adjacent therapeutic areas.
Essential Requirements
- MD and PhD required with clinical subspecialty training in neurological diseases; deep expertise in neuromuscular disorders and gene therapies.
- 10–15+ years of experience in translational medicine, early clinical development, or experimental therapeutics.
- Proven success leading complex global programs and cross-functional scientific teams.
- Ability to shape development strategies, execute early clinical studies, and influence regulatory packages supporting differentiation.
- Experience in a pharmaceutical/biotech company strongly preferred.
Desirable Requirements
- Direct people management experience.
Benefits (explicitly stated)
- Performance-based cash incentive; eligibility for annual equity awards (level-dependent).
- US-based benefits: health, life and disability; 401(k) with company contribution and match; other benefits; generous time off (vacation, personal days, holidays, and other leaves).
Application instructions
- For reasonable accommodations: e-mail [email protected] or call +1(877)395-2339; include the job requisition number.