Head of Clinical Excellence & Innovation - Inflammation & Immunology

Role Summary

Head of Clinical Excellence & Innovation – Inflammation & Immunology (I&I). Based in Cambridge, Massachusetts. Leads clinical innovation and excellence across Pfizer’s global I&I portfolio, shaping vision for clinical program performance and leveraging technology, data, and advanced strategies to accelerate development of transformative therapies in I&I.

Responsibilities

• Strategic Oversight & Vision: Shape and drive strategic direction for I&I clinical programs, championing innovative trial designs while upholding scientific rigor and regulatory excellence.
• Team Leadership & Culture: Inspire, mentor, and develop clinical leaders and scientists in I&I drug development; manage physicians and clinical scientists who do not report directly to other I&I development heads.
• Technology & Data Leadership: Integrate AI, digital health solutions, and advanced analytics to transform trial operations and empower data-driven decision-making.
• Process Optimization: Identify and scale best practices to streamline processes, boost operational efficiency, and build a flexible clinical infrastructure.
• External Engagement: Represent Pfizer at scientific conferences, regulatory forums, and partner/investor engagements; cultivate relationships with KOLs, CROs, academics, and regulators.
• Cross-Functional Partnership: Align clinical strategies with Medical Affairs, Regulatory, Safety, Operations, and Business Development.
• Industry Foresight: Monitor scientific and competitive landscape; leverage emerging technologies to inform Pfizer’s I&I clinical strategy.

Qualifications

• M.D. with at least 10 years’ experience leading I&I clinical trials.
• Proven success in I&I clinical project/program management in both large pharma and biotech environments.
• Deep understanding of I&I drug development, protocol writing, study conduct, data analysis, and regulatory submissions.
• Strong leadership and interpersonal skills; ability to mentor teams and collaborate with diverse stakeholders.
• Expertise in process improvement, change management, and digital transformation in clinical research.
• Experience with global I&I regulatory submissions and interactions with major regulatory agencies.
• Experience engaging with CROs, KOLs, regulators, and the broader I&I research community.
• Track record of leveraging data, technology, and innovative approaches to scale clinical operations and deliver patient value.

Skills

• Clinical development leadership
• Program design and execution
• Analytics, AI, and digital health integration
• Data integrity and data quality management
• Cross-functional collaboration and stakeholder management

Education

• MD or equivalent medical degree

Additional Requirements

• Relocation assistance may be available based on business needs and eligibility.