Head of AI Clinical Excellence
Pfizer
August 24, 2026
Remote friendly (Pennsylvania, United States)
United States
Clinical Research and Development
Role Summary
You will lead the strategic and hands-on application of Artificial Intelligence (AI) across the Clinical Development lifecycle, partnering across Clinical Development, Clinical Operations, Biostatistics, Data Science, Medical Affairs, Regulatory Affairs, and Digital to scale AI-driven capabilities that improve trial design, data review, execution, operational efficiency, decision-making, and regulatory readiness.
Role Responsibilities
- Develop and execute an enterprise strategy for AI-enabled Clinical Excellence.
- Identify high-value AI opportunities to accelerate timelines, improve quality, reduce operational burden, and enhance decision-making.
- Serve as a trusted advisor to senior leaders on emerging AI capabilities and industry trends.
- Drive AI adoption across study design, protocol optimization, feasibility, recruitment, execution, and clinical data review.
- Lead AI-enabled approaches for trial performance, operational excellence, and portfolio decisions; enable predictive and prescriptive analytics.
- Partner to design, build, validate, and deploy AI tools and platforms; establish scalable frameworks integrating into workflows.
- Develop agentic AI, generative AI, predictive analytics, and workflow automation solutions.
- Provide regulatory expertise for AI/ML/advanced analytics; partner to establish governance, validation, and risk management; monitor guidance/standards.
- Lead cross-functional teams; drive adoption via education and change management.
- Represent the organization in forums and conferences; build external partner relationships.
Minimum Qualifications
- MD with 4+ years relevant experience; or PhD with 5+ years; or MS with 7+ years (pharma/biotech/CRO/regulatory/healthcare).
- Experience designing/deploying AI/ML/advanced analytics in clinical research.
- Experience supporting clinical development/operations/science/data review/regulatory science.
- Lead cross-functional programs; strong GCP and regulatory understanding.
- Excellent communication and executive influencing.
Preferred Qualifications
- Expertise in Clinical Development/Oncology/Regulatory Science/Data Science/Clinical Informatics.
- Experience with LLMs, generative AI, agentic AI, or workflow automation in regulated environments.
- Experience interacting with global regulators (e.g., FDA/EMA/MHRA/PMDA/Health Canada); enterprise AI transformation.
Compensation/Benefits (as stated)
- Annual base salary: $176,600–$294,300; bonus target 20% of base; eligible long-term incentive.
- 401(k) with matching and additional retirement contribution; paid vacation/holidays/personal days; caregiver/parental and medical leave; medical, dental, vision.
Work Requirements (as stated)
- Occasional travel; hybrid role averaging 2.5 days/week on-site within commuting distance.
You will lead the strategic and hands-on application of Artificial Intelligence (AI) across the Clinical Development lifecycle, partnering across Clinical Development, Clinical Operations, Biostatistics, Data Science, Medical Affairs, Regulatory Affairs, and Digital to scale AI-driven capabilities that improve trial design, data review, execution, operational efficiency, decision-making, and regulatory readiness.
Role Responsibilities
- Develop and execute an enterprise strategy for AI-enabled Clinical Excellence.
- Identify high-value AI opportunities to accelerate timelines, improve quality, reduce operational burden, and enhance decision-making.
- Serve as a trusted advisor to senior leaders on emerging AI capabilities and industry trends.
- Drive AI adoption across study design, protocol optimization, feasibility, recruitment, execution, and clinical data review.
- Lead AI-enabled approaches for trial performance, operational excellence, and portfolio decisions; enable predictive and prescriptive analytics.
- Partner to design, build, validate, and deploy AI tools and platforms; establish scalable frameworks integrating into workflows.
- Develop agentic AI, generative AI, predictive analytics, and workflow automation solutions.
- Provide regulatory expertise for AI/ML/advanced analytics; partner to establish governance, validation, and risk management; monitor guidance/standards.
- Lead cross-functional teams; drive adoption via education and change management.
- Represent the organization in forums and conferences; build external partner relationships.
Minimum Qualifications
- MD with 4+ years relevant experience; or PhD with 5+ years; or MS with 7+ years (pharma/biotech/CRO/regulatory/healthcare).
- Experience designing/deploying AI/ML/advanced analytics in clinical research.
- Experience supporting clinical development/operations/science/data review/regulatory science.
- Lead cross-functional programs; strong GCP and regulatory understanding.
- Excellent communication and executive influencing.
Preferred Qualifications
- Expertise in Clinical Development/Oncology/Regulatory Science/Data Science/Clinical Informatics.
- Experience with LLMs, generative AI, agentic AI, or workflow automation in regulated environments.
- Experience interacting with global regulators (e.g., FDA/EMA/MHRA/PMDA/Health Canada); enterprise AI transformation.
Compensation/Benefits (as stated)
- Annual base salary: $176,600–$294,300; bonus target 20% of base; eligible long-term incentive.
- 401(k) with matching and additional retirement contribution; paid vacation/holidays/personal days; caregiver/parental and medical leave; medical, dental, vision.
Work Requirements (as stated)
- Occasional travel; hybrid role averaging 2.5 days/week on-site within commuting distance.