Head of AI Clinical Excellence
Pfizer
August 24, 2026
Remote friendly (Cambridge, MA)
United States
Clinical Research and Development
Role Summary
- Hands-on, proactive strategic leader advancing AI across the Clinical Development lifecycle; partner to identify, develop, and scale AI-driven capabilities to improve trial design, data review, execution, efficiency, decision-making, and regulatory readiness.
Responsibilities
Strategic AI Leadership
- Execute enterprise strategy for AI-enabled Clinical Excellence across Clinical Development.
- Identify high-value AI opportunities to accelerate timelines, improve quality, reduce operational burden, and enhance decision-making.
- Advise senior leaders on emerging AI capabilities and industry trends.
Clinical Development Innovation
- Drive AI adoption across study design, protocol optimization, feasibility, patient recruitment, trial execution, and clinical data review.
- Lead AI-enabled approaches to improve trial performance, operational excellence, and portfolio decisions.
- Enable predictive/prescriptive analytics for program and study decisions.
AI Product Development and Deployment
- Partner to design, build, validate, and deploy AI tools/platforms.
- Establish scalable frameworks integrating into clinical workflows.
- Develop agentic AI, generative AI, predictive analytics, and workflow automation for clinical operations.
Regulatory/Governance Leadership
- Advise on global regulatory expectations for AI/ML/advanced analytics in drug development.
- Partner on AI governance, validation approaches, and risk management.
- Monitor evolving health authority guidance.
Minimum Qualifications
- MD + 4+ years OR PhD + 5+ years OR MS + 7+ years in relevant clinical/pharma/tech fields.
- Experience designing/implementing AI/ML/advanced analytics in clinical research.
- Experience supporting clinical development/operations/data review/regulatory science.
- Led cross-functional clinical, regulatory, scientific, and technical programs.
- Strong GCP/clinical trial/regulatory understanding; translate challenges into scalable solutions; excellent communication/influencing.
Preferred Qualifications
- Expertise in Clinical Development/Oncology/Regulatory Science/Data Science/Clinical Informatics.
- Experience with LLMs, generative/agentic AI, workflow automation in regulated environments.
- Familiarity with emerging AI regulatory frameworks; interaction with global agencies.
Other
- Occasional travel; hybrid role (on-site ~2.5 days/week).
- Base salary: $176,600–$294,300; bonus target 20%; benefits include 401(k) match and healthcare/paid leave.
- Hands-on, proactive strategic leader advancing AI across the Clinical Development lifecycle; partner to identify, develop, and scale AI-driven capabilities to improve trial design, data review, execution, efficiency, decision-making, and regulatory readiness.
Responsibilities
Strategic AI Leadership
- Execute enterprise strategy for AI-enabled Clinical Excellence across Clinical Development.
- Identify high-value AI opportunities to accelerate timelines, improve quality, reduce operational burden, and enhance decision-making.
- Advise senior leaders on emerging AI capabilities and industry trends.
Clinical Development Innovation
- Drive AI adoption across study design, protocol optimization, feasibility, patient recruitment, trial execution, and clinical data review.
- Lead AI-enabled approaches to improve trial performance, operational excellence, and portfolio decisions.
- Enable predictive/prescriptive analytics for program and study decisions.
AI Product Development and Deployment
- Partner to design, build, validate, and deploy AI tools/platforms.
- Establish scalable frameworks integrating into clinical workflows.
- Develop agentic AI, generative AI, predictive analytics, and workflow automation for clinical operations.
Regulatory/Governance Leadership
- Advise on global regulatory expectations for AI/ML/advanced analytics in drug development.
- Partner on AI governance, validation approaches, and risk management.
- Monitor evolving health authority guidance.
Minimum Qualifications
- MD + 4+ years OR PhD + 5+ years OR MS + 7+ years in relevant clinical/pharma/tech fields.
- Experience designing/implementing AI/ML/advanced analytics in clinical research.
- Experience supporting clinical development/operations/data review/regulatory science.
- Led cross-functional clinical, regulatory, scientific, and technical programs.
- Strong GCP/clinical trial/regulatory understanding; translate challenges into scalable solutions; excellent communication/influencing.
Preferred Qualifications
- Expertise in Clinical Development/Oncology/Regulatory Science/Data Science/Clinical Informatics.
- Experience with LLMs, generative/agentic AI, workflow automation in regulated environments.
- Familiarity with emerging AI regulatory frameworks; interaction with global agencies.
Other
- Occasional travel; hybrid role (on-site ~2.5 days/week).
- Base salary: $176,600–$294,300; bonus target 20%; benefits include 401(k) match and healthcare/paid leave.