Global Safety Officer (Medical Director / Senior Medical Director)

Role: Serve as the core medical safety expert and strategic safety lead for Kymera's clinical development programs, overseeing safety from early trials through regulatory submission and post-marketing. Responsibilities include developing safety strategies, leading benefit-risk assessments, managing signal detection activities, authoring safety documentation for regulatory submissions, and representing patient safety in interactions with health authorities and external safety committees. Collaborate closely with Clinical Development, Regulatory, Biostatistics, Clinical Pharmacology, and Quality teams. Requirements: MD or equivalent, 3-6+ years in pharmacovigilance or clinical development with safety focus, strong knowledge of global PV regulations (FDA, EMA, ICH), hands-on experience with signal detection, safety reporting, risk management plans, and regulatory safety documentation. Demonstrated ability to synthesize complex safety data, communicate effectively with cross-functional teams, and operate efficiently in a fast-paced biotech setting. Preferred: experience in immunology, inflammation, oncology, small molecules, or targeted protein degraders; prior support for NDA/BLA safety submissions; board certification in relevant clinical specialty. High-Value: strategic pharmacovigilance leadership in a clinical-stage biotech developing innovative degraders, with a focus on immuno-oncology or immunology; involvement across full lifecycle safety management; regulatory interface experience. WorkSetup: not specified.