Global HEOR AD povetacicept

Role Summary

Global Health Economics & Outcomes Research (HEOR) Associate Director role in Vertex’s HEOR group in Boston, MA, focusing on povetacicept, a dual inhibitor of the BAFF and APRIL pathways, currently in phase III. Lead shaping and execution of HEOR strategies to optimize the asset’s value proposition and supporting evidence. This position reports to the Senior Director, Global HEOR, Kidney.

Responsibilities

• Leads others to execute complex HEOR evidence generation including cost-effectiveness analyses and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient-reported outcomes measure development and validation, and other research as needed to support the asset value.
• Gathers and synthesizes insights from payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning.
• Applies best practices to provide key input to the design of Vertex observational research studies.
• Collaborates with the medical communications teams on publication strategy and ensures that dissemination of HEOR evidence is timely and has maximum impact.
• Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative.

Skills

• Strong track record of publication in peer-reviewed journals.
• Provides technical expertise in HEOR and can formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices.
• Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences.
• Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies.
• Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct.

Education

• Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline.
• Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience.