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Global ERP Operations Lead, SAP Platform

Amgen
September 06, 2026
Full-time
Remote friendly (United States)
Worldwide
IT
Role: Global ERP Operations Lead responsible for the stability, performance, and continuous improvement of Amgen’s SAP (S/4HANA) platform. Responsibilities: oversee global ERP run operations ensuring high availability, security, compliance (GxP, SOX, GDPR), and performance; implement AI-enabled Operations and AIOps for resilience and efficiency; define KPIs and SLAs; lead automation, standardization, and modernization initiatives; manage security, access, and patching; lead and develop a global team; collaborate with solution, infrastructure, and delivery teams. Qualifications: Bachelor’s degree with 6+ years of experience or equivalent, with 10+ years preferred; deep expertise in SAP S/4HANA, SAP BTP, and enterprise system integrations; proven experience managing SAP landscapes at scale; knowledge of cloud infrastructure (AWS), automation, ITIL, and regulatory compliance in GxP environments; strong leadership and stakeholder management skills. HighValue: enterprise SAP landscape, global operations, automation, cloud infrastructure (AWS), compliance frameworks, cross-functional collaboration, continuous improvement, focus on operational excellence.