Global Development Product Lead (Sr Director)

Responsibilities:
- Lead multiple (~1–3) cross-functional oncology product teams from pre-clinical candidate nomination (CAN) through Phase 1–2 clinical development and proof of concept (POC), with potential handoff to late-stage Oncology Development (typically Phase 3).
- Collaborate with functional experts to integrate an end-to-end cross-functional molecule strategy and risk mitigation plan; deliver data-driven milestones via risk identification and mitigation.
- Support clinical trials and early-development/lead-development strategy across multiple Pfizer Oncology functions; represent the program with the external clinical community.
- Develop the clinical development plan from first-in-human through POC, including assessment of appropriate combinations and evaluation of predictive and pharmacodynamics biomarker plans.
- Ensure clinical plans include clinical expertise and medical monitoring of clinical trials.
- Lead, develop, and execute strategic development for early development assets; drive an integrated product plan addressing near-term technical uncertainties and aligning with future pivotal development and commercialization.
- Ensure timely execution and delivery of product milestones within budget.
- Communicate with executive management and governance committees; provide clear product presentations and recommendations.
- Collaborate with partners on co-development programs to deliver a shared global product strategy (when applicable).
- Set team objectives, prioritize tasks, and ensure adherence to the plan and strategy; proactively identify and resolve issues and develop contingency plans.
- Oversee early development assets’ development within indications (typically at least two clinical programs) and consult on multiple research projects.
- Work across multifunctional teams (Product Team, Global Development Team, Study team).
- Oversee development and management of clinical protocols/amendments, investigator brochures, clinical study reports, statistical analysis plans, and regulatory documents.
- Provide leadership to early-stage clinical scientists in a matrix environment; work with cross-functional colleagues to influence emerging targets, priorities, and program status.
- Implement PK-guided dose escalation, early combination strategies, and innovations on first-in-human oncology trials.
- Oversee evaluation of safety, pharmacology, and efficacy data from ongoing/completed studies.
- Oversee manuscripts, abstracts, and presentations for scientific meetings/advisory boards; conduct literature reviews and prepare summaries.
- Serve as a medical resource for design and interpretation of clinical and preclinical programs.
- Coordinate regular interactions (at least quarterly and as needed) with clinical trials networks and KOL advisory boards to consider/implement feedback.
- Drive innovations in early clinical development, including translational oncology and precision medicine approaches.
- Translate early preclinical discovery into therapeutic candidates via cross-functional collaboration.
- Coordinate with business development on strategic external collaborations and new research/program initiatives.

Qualifications / Skills:
- MD or MD-PhD with 5+ years of industry experience (required).
- Oncology drug development experience; track record in oncology clinical research including early-phase drug development (preferred).
- Clinical oncology experience; board certification in oncology (preferred).
- Significant industry leadership experience in clinical, translational, or basic research in biomedical sciences or drug-development-related disciplines.
- Knowledge of related disciplines (e.g., biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences).
- Demonstrated scientific productivity (publications, abstracts, etc.).
- Proven scientific writing and strong communication skills.
- Proven leadership skills; ability to defend the clinical plan at governance meetings (essential).
- Ability to adapt to a fast-paced, changing environment.
- Demonstrated effective leadership in cross-functional and matrix teams; experience seeking and maintaining alignment with cross-functional leaders.
- Passion for helping patients with cancer and for the science of oncology.
- Proactive, strategic, data-driven decision-making.
- Ability to focus and motivate a matrix organization with multiple stakeholders.
- Strong verbal, written, and presentation communication skills.
- Staff management and mentoring experience.
- Highly collaborative relationship-building skills with internal leaders, external partners, and investigators/medical professionals.
- Strong leadership presence and ability to work effectively with other leaders.
- Team player in both leadership and contributor roles.
- Global perspective and ability to work across diverse cultures and geographies.