Global Development Lead, Internal Medicine, Sr. Director (MD)
Pfizer
August 10, 2026
Remote friendly (La Jolla, CA)
United States
Clinical Research and Development
Responsibilities
- Serve as clinical point of accountability for assigned Internal Medicine assets; lead cross-functional Clinical Development Teams (clinical, clinical pharmacology, statistics, safety, commercial, patient access, operations).
- Create and gain endorsement for the Clinical Development Plan and associated protocol design documents; partner throughout study lifecycle.
- Lead obesity portfolio clinical leadership as needed (trial design, execution, reporting).
- Lead governance reviews with trial clinicians; provide therapy area/indication expertise (CRF design, signal interpretation, adverse event contextualization).
- Drive submission strategy and deliverables (IAP/IARP, submission TLFs; SCE/SCS; DSUR, PBRER; safety narrative plan; product label development/maintenance).
- Contribute to target product profiles; support product defense.
- Partner with external stakeholders (e.g., advisory boards, steering committees, DMC, adjudication committees, patients/advocates).
- Support trial-level statistical analysis plan, TLFs, database release; review IIR proposals.
Basic Qualifications
- Education: MD or DO.
- Experience: chronic weight management/endocrinology/internal medicine; Phase 1–3 clinical development and translational medicine; 8+ years in clinical R&D (academia and/or biopharma).
- Extensive knowledge of global/regional regulation, ICH/GCP, adverse event management.
- Demonstrated medical/administrative/project management; effective verbal/written communication; manage/train large teams (designing/launching large teams preferred).
Competencies (required)
- Leadership, influence in matrix environments, accountability, conflict management, team building, and ability to deliver amid change.
Benefits/Compensation (as stated)
- Base salary range: $274,500–$457,500; bonus target 25%; eligibility for long-term incentive; 401(k) with matching and additional retirement contribution; paid vacation/holiday/personal days; paid caregiver/parental and medical leave; medical/prescription/dental/vision.
Work
- Up to 30% travel; hybrid role (on-site ~2.5 days/week).
- Serve as clinical point of accountability for assigned Internal Medicine assets; lead cross-functional Clinical Development Teams (clinical, clinical pharmacology, statistics, safety, commercial, patient access, operations).
- Create and gain endorsement for the Clinical Development Plan and associated protocol design documents; partner throughout study lifecycle.
- Lead obesity portfolio clinical leadership as needed (trial design, execution, reporting).
- Lead governance reviews with trial clinicians; provide therapy area/indication expertise (CRF design, signal interpretation, adverse event contextualization).
- Drive submission strategy and deliverables (IAP/IARP, submission TLFs; SCE/SCS; DSUR, PBRER; safety narrative plan; product label development/maintenance).
- Contribute to target product profiles; support product defense.
- Partner with external stakeholders (e.g., advisory boards, steering committees, DMC, adjudication committees, patients/advocates).
- Support trial-level statistical analysis plan, TLFs, database release; review IIR proposals.
Basic Qualifications
- Education: MD or DO.
- Experience: chronic weight management/endocrinology/internal medicine; Phase 1–3 clinical development and translational medicine; 8+ years in clinical R&D (academia and/or biopharma).
- Extensive knowledge of global/regional regulation, ICH/GCP, adverse event management.
- Demonstrated medical/administrative/project management; effective verbal/written communication; manage/train large teams (designing/launching large teams preferred).
Competencies (required)
- Leadership, influence in matrix environments, accountability, conflict management, team building, and ability to deliver amid change.
Benefits/Compensation (as stated)
- Base salary range: $274,500–$457,500; bonus target 25%; eligibility for long-term incentive; 401(k) with matching and additional retirement contribution; paid vacation/holiday/personal days; paid caregiver/parental and medical leave; medical/prescription/dental/vision.
Work
- Up to 30% travel; hybrid role (on-site ~2.5 days/week).