Global Development Lead, Internal Medicine, Sr. Director (MD)
Pfizer
August 10, 2026
Remote friendly (Pennsylvania, United States)
United States
Clinical Research and Development
Responsibilities:
- Serve as single clinical point of accountability for clinical development of assigned internal medicine assets; lead cross-functional Clinical Development Team (clinical, clinical pharmacology, statistics, safety, commercial, patient access, operations) to design, execute, and interpret studies for worldwide regulatory submissions.
- Create and gain endorsement for the Clinical Development Plan and associated protocol design documents; ensure trial feasibility and optimized operational execution.
- Lead pediatric investigation plan/study plan and protocol design; develop submission deliverables (IAP, IARP, submission TLFs) including SCE and SCS.
- Provide therapy area/indication expertise (CRF design, signal interpretation, adverse event contextualization); partner on trial-level statistical analysis plan, TLFs/table-listings-figures, and database release.
- Support regulatory submissions and disclosures/defense (e.g., DSUR, PBRER), safety narrative plan review/approval, and product label development/maintenance.
- Engage external stakeholders (ad boards, steering committees, DMC, adjudication committees, patients/patient advocates) to drive clinical development strategy.
Qualifications/Required skills:
- MD or DO.
- 8+ years relevant experience in clinical research/development (academia and/or biopharma); Phase 1–3 clinical development and translational medicine experience.
- Background in chronic weight management, endocrinology, or internal medicine; extensive knowledge of clinical development, global/regional regulation, ICH/GCP, adverse event management.
- Demonstrated clinical/medical, project/administrative management, and effective verbal/written communication skills; experience managing/training large teams.
Benefits (explicitly stated): Base salary $274,500–$457,500; bonus target 25%; participation in share-based long-term incentive; comprehensive health/401(k) and other leave/vacation benefits.
Application instructions: Not provided in text.
- Serve as single clinical point of accountability for clinical development of assigned internal medicine assets; lead cross-functional Clinical Development Team (clinical, clinical pharmacology, statistics, safety, commercial, patient access, operations) to design, execute, and interpret studies for worldwide regulatory submissions.
- Create and gain endorsement for the Clinical Development Plan and associated protocol design documents; ensure trial feasibility and optimized operational execution.
- Lead pediatric investigation plan/study plan and protocol design; develop submission deliverables (IAP, IARP, submission TLFs) including SCE and SCS.
- Provide therapy area/indication expertise (CRF design, signal interpretation, adverse event contextualization); partner on trial-level statistical analysis plan, TLFs/table-listings-figures, and database release.
- Support regulatory submissions and disclosures/defense (e.g., DSUR, PBRER), safety narrative plan review/approval, and product label development/maintenance.
- Engage external stakeholders (ad boards, steering committees, DMC, adjudication committees, patients/patient advocates) to drive clinical development strategy.
Qualifications/Required skills:
- MD or DO.
- 8+ years relevant experience in clinical research/development (academia and/or biopharma); Phase 1–3 clinical development and translational medicine experience.
- Background in chronic weight management, endocrinology, or internal medicine; extensive knowledge of clinical development, global/regional regulation, ICH/GCP, adverse event management.
- Demonstrated clinical/medical, project/administrative management, and effective verbal/written communication skills; experience managing/training large teams.
Benefits (explicitly stated): Base salary $274,500–$457,500; bonus target 25%; participation in share-based long-term incentive; comprehensive health/401(k) and other leave/vacation benefits.
Application instructions: Not provided in text.