Global Development Lead, Internal Medicine (MD, Sr. Director)
Pfizer
August 13, 2026
Remote friendly (La Jolla, CA)
United States
Clinical Research and Development
Role Responsibilities
- Lead cross-functional Clinical Development Team to design, execute, and interpret studies supporting worldwide regulatory submissions for assigned asset(s).
- Own the Clinical Development Plan and related protocol design documents; ensure feasibility and optimized operational execution with trial clinicians.
- Develop global clinical development strategy (incl. pediatric investigation plan/study plan) to secure approval and reimbursement globally (incl. China and Japan).
- Provide therapy area/indication expertise for clinical review (CRF design, signal interpretation, adverse event contextualization).
- Contribute to target product profile(s) and regulatory deliverables (e.g., SCE/SCS, IAP/IARP, submission TLFs, IIR proposals, DSUR, PBRER, SCE/SCS, safety narrative plan).
- Partner with statistics/programming on trial-level statistical analysis plan, TLFs, listings-figures, and database release.
- Support product label development/maintenance and submission data interpretation/communication.
- Engage external stakeholders (e.g., DMC, Steering/Ad boards, adjudication committees, patients) to generate insights for clinical strategy and PDD development.
Qualifications / Required Skills
- MD or DO.
- Endocrinologist or internal medicine physician with cardiometabolic late-stage development experience (incl. type 2 diabetes).
- 8+ years clinical research & development experience; track record in academia and/or biopharma.
- Extensive knowledge of clinical development, global/regional regulation, ICH/GCP, and adverse event management.
- Strong clinical/medical, administrative, and project management; effective written/verbal communication; experience managing/training large clinical teams.
- Ability to influence in a complex matrix environment; strong leadership and conflict management.
Preferred
- Experience designing and launching large teams.
Benefits / Other
- Up to 30% travel; hybrid role (on-site ~2.5 days/week).
- Base salary: $274,500–$457,500 (Tampa: $228,700–$381,100). Bonus target 25% of base and eligibility for long-term incentive.
- Benefits include 401(k) with matching and additional retirement contribution, paid time off, caregiver/parental and medical leave, and medical/prescription/dental/vision coverage.
Application Instructions: None provided.
- Lead cross-functional Clinical Development Team to design, execute, and interpret studies supporting worldwide regulatory submissions for assigned asset(s).
- Own the Clinical Development Plan and related protocol design documents; ensure feasibility and optimized operational execution with trial clinicians.
- Develop global clinical development strategy (incl. pediatric investigation plan/study plan) to secure approval and reimbursement globally (incl. China and Japan).
- Provide therapy area/indication expertise for clinical review (CRF design, signal interpretation, adverse event contextualization).
- Contribute to target product profile(s) and regulatory deliverables (e.g., SCE/SCS, IAP/IARP, submission TLFs, IIR proposals, DSUR, PBRER, SCE/SCS, safety narrative plan).
- Partner with statistics/programming on trial-level statistical analysis plan, TLFs, listings-figures, and database release.
- Support product label development/maintenance and submission data interpretation/communication.
- Engage external stakeholders (e.g., DMC, Steering/Ad boards, adjudication committees, patients) to generate insights for clinical strategy and PDD development.
Qualifications / Required Skills
- MD or DO.
- Endocrinologist or internal medicine physician with cardiometabolic late-stage development experience (incl. type 2 diabetes).
- 8+ years clinical research & development experience; track record in academia and/or biopharma.
- Extensive knowledge of clinical development, global/regional regulation, ICH/GCP, and adverse event management.
- Strong clinical/medical, administrative, and project management; effective written/verbal communication; experience managing/training large clinical teams.
- Ability to influence in a complex matrix environment; strong leadership and conflict management.
Preferred
- Experience designing and launching large teams.
Benefits / Other
- Up to 30% travel; hybrid role (on-site ~2.5 days/week).
- Base salary: $274,500–$457,500 (Tampa: $228,700–$381,100). Bonus target 25% of base and eligibility for long-term incentive.
- Benefits include 401(k) with matching and additional retirement contribution, paid time off, caregiver/parental and medical leave, and medical/prescription/dental/vision coverage.
Application Instructions: None provided.