Executive Medical Director, Clinical Development, Neurodegeneration

About The Role:
The Executive Medical Director will develop and execute the Neurology strategy and drive clinical programs for neurodegenerative diseases.

Responsibilities:
- Serve as the clinical/program lead for development of clinical research strategies, clinical development plans, and independent direction of Phase 1–4 clinical studies within cross-functional teams (clinical operations, preclinical/clinical pharmacology, biometrics, regulatory, drug safety, CMC)
- Provide medical oversight of clinical research studies; deliver medical input/decisions to study teams, external partners, and clinical sites
- Establish/approve scientific methods for clinical protocol design and implementation, data collection systems, data analysis, and final reports
- Partner with Drug Safety Pharmacovigilance on adverse event reporting and safety monitoring committees (as required)
- Coordinate and develop content for reports and submissions to regulatory/other agencies
- Participate in the Neurology Therapeutic Area Strategy Group to evolve R&D strategy for new targets, research programs, and platform development
- Collaborate with Research, Preclinical Development, and Experimental Medicine to vet/develop biomarkers for evaluation of novel molecules
- Partner with Business Development on assessment of external innovation
- Drive strategic direction, oversee clinical phases, and ensure design/implementation of clinical plans and result communication
- Lead planning/execution of global clinical development projects in compliance with GxP and regulatory requirements
- Create/foster relationships with external scientific leaders and investigators
- Support as a subject matter expert relevant US/global regulatory submission documents
- Lead/support R&D process improvement; supervise monitoring procedures and data collection
- Monitor clinical trials directly/indirectly (operational teams, QA systems, CROs)
- Contribute to external publications/presentations; anticipate strategic opportunities and recommend solutions
- Manage clinical development organization members/functions in a matrix environment (as applicable)

Qualifications & Requirements:
- MD (or equivalent) with accredited residency training and board certification in Neurology; Fellowship training preferred; 8+ years clinical drug development experience (Phase 1–3) in pharma/biotech, including significant senior leadership experience
- Advanced degree (MS/PhD) in a relevant scientific discipline preferred
- Demonstrated leadership of clinical programs in neurodegenerative diseases; recent experience developing drugs for Alzheimer disease/neurocognitive syndromes and Parkinson disease/related disorders
- Desired: experience developing treatment modalities (small molecules and biologic/genetic therapies)
- Mandatory: extensive clinical drug development knowledge (clinical development planning, US/global regulatory requirements and submission standards, study design, biostatistics, GCP; oversight of internal/CRO conduct, data collection/analysis, report writing, and scientific presentation across early/late phases)
- Ability to operate effectively in a multi-level matrix environment with internal/external stakeholders
- First-hand clinical and research expertise in neurology therapeutic area/diseases
- Track record partnering with multiple stakeholders (collaboration partners, scientific orgs, patient advocacy)
- Strong expertise in leading-edge clinical drug development theories/techniques; problem-solving in novel/complex situations
- Ability to influence internal/external business/industry issues impacting Neurocrine
- Exceptional analytical/critical thinking; communication; accountability; interpersonal/organizational skills; cross-functional leadership

Benefits:
- Annual bonus with a target of 35% of earned base salary
- Eligibility for equity-based long-term incentive program
- Retirement savings plan (with company match); paid vacation/holiday/personal days; paid caregiver/parental and medical leave
- Health benefits (medical, prescription drug, dental, vision)
- Annual base salary range: $322,800.00–$440,000.00

Application Instructions:
- Encouraged to apply even if experience/qualifications don’t fully match the job description.